Antazol Nasal Drop 0.05%

✔️ Uses of Antazol Nasal Drop 0.05%

• Nasal Congestion
• Cold
• Rhinitis
• Sinusitis

✔️ How Xylometazoline Hydrochloride works

Xylometazoline  Hydrochloride is a decongestant. It works by narrowing the small blood vessels which provide temporary relief from inflammation (redness and swelling) and discomfort.

✔️ Side Effects of Antazol Nasal Drop

• Burning sensation
• Stinging
• Headache
• Increased blood pressure
• Dryness in the nose
• Dry mouth
• Increased heart rate
• Runny nose
• Sneezing

✔️ Quick Suggestions:

• Taking Antazol Nasal Drops for more than 7 days in a row may cause stuffiness.
• Taking Antazol Nasal Drops for more than 7 days in a row may cause stuffiness.
• After 28 days, discard the bottle of Antazol Nasal Drop for hygiene reasons.
• Quit smoking and stay away from passive smoking. Smoking also lowers the medication's efficacy.
• To assist relieve congestion and lubricate the throat, drink plenty of fluids when using Xylomist 0.1% Nasal Drops 10 ml.
• To improve your respiratory muscles and increase your immune system, consume a nutritious diet and exercise regularly.
• Breathing exercises will teach you how to transfer more air into and out of your lungs.
• If you have an allergic reaction to Antazol Nasal Drop, seek medical attention right away. Hives, rash, facial and lip swelling, and difficulty breathing, and/or speaking are all symptoms.

✔️ Indication of Antazol Nasal Drop 0.05%

Xylometazoline Hydrochloride belongs to the nasal decongestants class. It is used to relieve the irritation and inflammation caused by nose blocks and colds. Xylometazoline Hydrochloride is used to treat mucosal inflammation caused by colds, allergic rhinitis (nasal inflammation), and sinusitis (flaring up of the sinuses). Allergies cause allergic rhinitis, which is a swelling of the inside of the nose and nostrils. Sinusitis is the inflammation of the nasal sinuses, which become clogged and blocked by mucous secretions and fluid.

✔️ Pharmacology

Nasal congestion is caused by a variety of etiologies, including rhinosinusitis and allergic or non-allergic rhinitis, resulting in congestion of the venous sinusoids lining the nasal mucosa. When -adrenergic receptors are activated, nasal mucosal blood vessels constrict, and nasal airflow is restored. The most abundantly expressed 1A- and 2B-adrenoceptors in the human nasal mucosa may play the most important role in vasoconstriction of the human nasal mucosa. Xylometazoline is a 2B-adrenoceptor agonist with affinity for 1A-, 2A-, 2C-, 1B-, and 1D-adrenoceptors. Xylometazoline increases nasal airflow volume while decreasing nasal resistance during inspiration and expiration. Xylometazoline had a significantly faster onset of action than oxymetazoline, another imidazoline nasal decongestant with a similar duration of action. In one study, subjects with nasal congestion reported relief from earache and sore throat in addition to nasal decongestion: This effect is thought to be mediated by oxymetazoline-inducing vasoconstriction of the nasal mucosa, which contains the venous sinuses. Nasal decongestion allows for nasal breathing, which relieves sore throat caused by mouth breathing, which dries and irritates the throat.

✔️ Dosage of Antazol Nasal Drop 0.05%

• Xylometazoline 0.05%: 2 or 3 drops in each nostril two or three times daily in children aged 6 to 12 years.
• Xylometazoline 0.05%: 1 drop in each nostril two or three times daily in children under the age of six.
• Infants under 3 months: Not to be used in infants under 3 months.

✔️ Administration of Antazol Nasal Drop 0.05%

• Check the label for directions before using this medicine.
• Insert the tip of the bottle into a nostril while closing the other nostril and instill the drops towards the sides of the nostril.
• Keep your head straight and breathe gently.
• Repeat the same process for the other nostril.
• If you have inserted the tip of the bottle inside your nose, then rinse the tip with warm water and dry it with a tissue.
• Avoid getting this medicine into your eyes.

✔️ Interaction

Increased heart rate or BP with sibutramine. Potentially Fatal: Hypertensive crisis with MAOIs.

✔️ Contraindications

Individuals who have had transsphenoidal hypophysectomy or surgery that exposed the dura mater should not use xylometazoline nasal drops. It is also not advised for those who are sensitive to Xylometazoline. Each Xylometazoline nasal drop should only be used by one person to avoid cross-infection. Decongestants should not be used for more than seven days in a row by patients.

✔️ Pregnancy & Lactation

C is the pregnancy category. Xylometazoline should not be used when pregnant. The use of Otrivin while nursing should be done exclusively under the supervision of a doctor.

✔️ Precautions & Warnings

• Xylometazoline Hydrochloride should only be used externally.
• Adults should not use Xylometazoline Hydrochloride nasal drops (0.1 percent) on children under the age of 12.
• Drops should not be used for an extended period of time in situations of chronic rhinitis. Hold your breath for a few moments. After using Xylometazoline Hydrochloride, make sure to tightly close the bottle.
• Long-term usage of the drops may result in rebound congestion and drug-induced rhinitis.
• During pregnancy, Antazol Nasal Drops should be used only when clearly needed. Discuss the risks and benefits with your doctor.
• Avoid using Antazol Nasal Drop if you are allergic to it
• Antazol Nasal Drops should be used with caution in patients with a known hypersensitivity disorder, acute angle-closure glaucoma, rhinitis sicca, atrophic rhinitis, prostate enlargement, pheochromocytoma, and any heart disease.

✔️ Storage Conditions

Keep out of direct sunlight. For hygienic concerns, do not use the bottle more than 28 days after it has been opened.