Antazol Nasal Drop 0.1%

✔️ Uses of Antazol Nasal Drop 0.1%

• Nasal Congestion
• Cold
• Rhinitis
• Sinusitis

✔️ How Xylometazoline Hydrochloride works

Xylometazoline  Hydrochloride is a decongestant. It works by narrowing the small blood vessels which provide temporary relief from inflammation (redness and swelling) and discomfort.

✔️ Side Effects of Antazol Nasal Drop

• Headache
• Nausea
• Application site burning
• Nasal Discomfort
• Nasal Dryness

✔️ Quick Suggestions:

• Taking Antazol Nasal Drops for more than 7 days in a row may cause stuffiness.
• Taking Antazol Nasal Drops for more than 7 days in a row may cause stuffiness.
• After 28 days, discard the bottle of Antazol Nasal Drop for hygiene reasons.
• If you have an allergic reaction to Antazol Nasal Drop, seek medical attention right away. Hives, rash, facial and lip swelling, and difficulty breathing, and/or speaking are all symptoms.

✔️ Indications of Antazol Nasal Drop 0.1%

Antazol Nasal Drop is used in-

• Colds, rhinitis, sinusitis, and headaches can all cause nasal congestion.
• Nasal congestion is associated with both tubal obstruction and serous otitis media.

✔️ Pharmacology

Nasal congestion is caused by a variety of etiologies, including rhinosinusitis and allergic or non-allergic rhinitis, resulting in congestion of the venous sinusoids lining the nasal mucosa. When -adrenergic receptors are activated, nasal mucosal blood vessels constrict, and nasal airflow is restored. The most abundantly expressed 1A- and 2B-adrenoceptors in the human nasal mucosa may play the most important role in vasoconstriction of the human nasal mucosa. Xylometazoline is a 2B-adrenoceptor agonist with affinity for 1A-, 2A-, 2C-, 1B-, and 1D-adrenoceptors. Xylometazoline increases nasal airflow volume while decreasing nasal resistance during inspiration and expiration. Xylometazoline had a significantly faster onset of action than oxymetazoline, another imidazoline nasal decongestant with a similar duration of action. In one study, subjects with nasal congestion reported relief from earache and sore throat in addition to nasal decongestion: This effect is thought to be mediated by oxymetazoline-inducing vasoconstriction of the nasal mucosa, which contains the venous sinuses. Nasal decongestion allows for nasal breathing, which relieves sore throat caused by mouth breathing, which dries and irritates the throat.

✔️ Dosage of Antazol Nasal Drop

• Adults: Xylometazoline 0.1%: two or three drops in each nostril two to three times per day. Children under the age of 12 should not be given xylometazoline 0.1%.
• Xylometazoline 0.05%: 2 or 3 drops in each nostril two or three times daily in children aged 6 to 12 years.
• Xylometazoline 0.05%: 1 drop in each nostril two or three times daily in children under the age of six.
• Infants under 3 months: Not to be used in infants under 3 months

✔️ Administration of Antazol Nasal Drop

The proper way to use the nasal spray:

• Before using the medication, shake the bottle.
• Before using the medication, thoroughly clean your nose.
• Close one nostril and insert the bottle tip into the other.
• Aim the spray at the sides of your nostrils, away from the cartilage that separates the two sides of your nose.
• Breathe out gently through your mouth, then repeat for the other nostril
• If used for more than 7 days in a row, it can aggravate nasal congestion (called rebound congestion).
• Do not share the bottle with anyone else so that you do not spread germs.
• Deep breathing should be avoided because it causes medication to return to the throat, making it less effective.

✔️ Interaction

Increased heart rate or BP with sibutramine. Potentially Fatal: Hypertensive crisis with MAOIs.

✔️ Contraindications

Individuals who have had transsphenoidal hypophysectomy or surgery that exposed the dura mater should not use xylometazoline nasal drops. It is also not advised for those who are sensitive to Xylometazoline. Each Xylometazoline nasal drop should only be used by one person to avoid cross-infection. Decongestants should not be used for more than seven days in a row by patients.

✔️ Pregnancy & Lactation

C is the pregnancy category. Xylometazoline should not be used when pregnant. The use of Otrivin while nursing should be done exclusively under the supervision of a doctor.

✔️ Precautions & Warnings

• Xylometazoline Hydrochloride should only be used externally.
• Adults should not use Xylometazoline Hydrochloride nasal drops (0.1 percent) on children under the age of 12.
• Drops should not be used for an extended period of time in situations of chronic rhinitis. Hold your breath for a few moments. After using Xylometazoline Hydrochloride, make sure to tightly close the bottle.
• Long-term usage of the drops may result in rebound congestion and drug-induced rhinitis.
• During pregnancy, Antazol Nasal Drops should be used only when clearly needed. Discuss the risks and benefits with your doctor.
• Avoid using Antazol Nasal Drop if you are allergic to it
• Not enough information is available on whether Antazol Nasal Drop is safe for use in children below 12 years of age. Avoid Xylometazoline Hydrochloride use in children below 12. Consult your physician before use.
• Antazol Nasal Drops should be used with caution in patients with a known hypersensitivity disorder, acute angle-closure glaucoma, rhinitis sicca, atrophic rhinitis, prostate enlargement, pheochromocytoma, and any heart disease.

✔️ Storage Conditions

Keep out of direct sunlight. For hygienic concerns, do not use the bottle more than 28 days after it has been opened.