Nasal Spray.
Generic Name: Beclomethasone dipropionate 50mcg metered dose (spray): aqueous suspension for nasal spray. 200 metered spray.
Manufacturer/Distributor: Square
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Indication
Sinusitis, Hay fever, Allergic and non-allergic rhinitis, Nasal Polyps (Postsurgical Prophylaxis), Vasomotor Rhinitis
Administration
Shake well before each use Before first use, prime pump by 6 actuations into air If not used for 7 days, reprime pump until fine spray appears
Adult Dose
Adults: The usual dosage is 1-2 inhalations in each nostril twice a day .
Child Dose
Children 12 Years of Age and Older: The usual dosage is 1-2 inhalations in each nostril twice a day . Children 6 to 12 Years of Age: Patients should be started with 1 inhalation in each nostril twice a day; patients with more severe symptoms may use 2 inhalations in each nostril. <6 years: Safety and efficacy not established
Contraindication
patients with a history of hyper-sensitivity to any of the components
Mode of Action
Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.
Precaution
Nasal passage infections and paranasal sinuses should be appropriately treated. Caution should be exercised whilst transferring patients from systemic steroid treatment to Beclometasone Dipropionate Aqueous Nasal Spray if there is doubt that their adrenal function is impaired. Systemic effects of nasal corticosteroids may occur particularly at high doses prescribed for prolonged periods. Growth retardation has been reported in children receiving nasal corticosteroids at licensed doses. Treatment with higher than recommended doses may result in clinically significant adrenal suppression. If there is evidence for higher than recommended doses being used then additional systemic corticosteroid cover should be considered during periods of stress or elective surgery. Lactation: Unknown whether distributed in breast milk; use caution
Side Effect
>10% Nasopharyngeal irritation (24%) 1-10% Headache (<5%),Nausea (<5%),Lightheadedness (<5%),Sneezing attacks after administration (4%),Nasal congestion (<3%),Nose bleeds (<3%),Rhinorrhea (<3%),Increased lacrimation (<3%),Epistaxis (<3%) Frequency Not Defined Nasal mucosa ulceration,Nasal septum perforation
Pregnancy Category Note
Pregnancy Category: C Lactation: Unknown whether distributed in breast milk; use caution
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