Neotison Nasal Spray

✔️ Uses of Neotison Nasal Spray

Fluticasone Furoate is used in the treatment of sneezing and runny nose due to allergies.

✔️ How does Neotison Nasal Spray work?

Fluticasone Furoate is a steroid that works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

✔️ Side Effects of Neotison Nasal Spray

• Nasal spray may cause dryness and increased nosebleeds.
• Common adverse events in inhalation capsule use: nasopharyngitis, bronchitis, upper respiratory tract infections, headaches.

✔️ Quick Suggestions:

• Shake the nasal spray bottle before using the medicine.
• Clean your nose thoroughly before using the medicine.
• Insert the bottle tip into one nostril.
• Close the other nostril.
• Direct the spray towards the sides of the nostril, away from the cartilage dividing the two sides of the nose.
• Breathe out gently through your mouth.
• Repeat the same process for the other nostril.
• Avoid deep breathing to prevent the medication from going back to the throat, ensuring it remains effective.
• Do not share the nasal spray bottle with anyone else to avoid spreading germs.
• Fluticasone Furoate should be avoided in patients with recent nasal ulcers, nasal surgery, or nasal trauma.

✔️ Allergy:

Allergy is an immune system response to foreign elements, known as "allergens," which are typically harmless to the body.

Nature of Allergens:

• Allergens can vary widely, including foods, pollen, pet dander, dust mites, insect stings, or certain medications.

Individual Variations:

• Allergic conditions differ from person to person.
• Some may experience allergies related to specific foods or seasonal factors like hay fever.
• Others may have reactions to environmental factors such as pollen or pet dander.

Immune System Response:

• The immune system mistakenly identifies allergens as harmful invaders.
• In response, the body releases chemicals, such as histamines, triggering allergy symptoms.

Common Allergies:

1. Seasonal Allergies (Hay Fever):
   • Caused by pollen from trees, grasses, and weeds.
2. Food Allergies:
   • Reactions to specific foods like nuts, shellfish, or dairy products.
3. Animal Allergies:
   • Allergic reactions to pet dander, saliva, or urine.
4. Insect Sting Allergies:
   • Reactions to bee stings or other insect bites.
5. Drug Allergies:
   • Adverse reactions to certain medications.

Symptoms:

• Symptoms vary based on the type of allergy but may include sneezing, itching, runny nose, swelling, hives, or more severe reactions like anaphylaxis.

Treatment:

• Management involves allergen avoidance, medications (antihistamines, decongestants), and in severe cases, allergen immunotherapy.

If you suspect allergies, consult with a healthcare professional for proper diagnosis and management.

✔️ Pharmacology

• Fluticasone furoate, a trifluoride corticosteroid, exhibits anti-inflammatory qualities.
• Acts on various inflammatory mediators and cell types, including mast cells, eosinophils, neutrophils, macrophages, and lymphocytes.

✔️ Dosage of Neotison Nasal Spray

Fluticasone Furoate Nasal Spray:

• Adults and children over 12 years: 2 sprays into each nostril, twice daily (max 4 sprays).
• Children 2-11 years: 1 spray into each nostril, once daily.

✔️ Direction for use:

1. Shake the bottle and remove the dust cap.
2. Hold the spray with the thumb underneath and the forefinger/middle finger on either side of the nozzle.
3. Administer 2 sprays into each nostril for adults; once daily, 1 spray for children 2-11 years.
4. Clean the nasal spray at least once a week.

✔️ Interaction

• Cytochrome P450 3A4 (CYP3A4) inhibitors may increase exposure to fluticasone furoate.
• Ritonavir should not be taken concurrently; caution with other potent CYP3A4 inhibitors.

✔️ Contraindications

Fluticasone Furoate nasal spray is not recommended for individuals allergic to any of its components.

✔️ Pregnancy & Lactation

• Not recommended during pregnancy; use only if benefits outweigh risks.
• Excretion in human breast milk is unknown; caution is advised during breastfeeding.

✔️ Precautions & Warnings

• Rare cases of acute hypersensitivity responses or contact dermatitis may occur.
• Potential for wheezing, nasal septum perforation, cataracts, glaucoma, and elevated intraocular pressure.
• Systemic effects increase with higher doses; avoid exceeding the prescribed dose.

✔️ Storage Conditions

Store at temperatures below 30°C, avoid refrigeration, sunlight, and dampness. Keep out of children's reach.