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Indications
The medication oxymetazoline hydrochlorid is used to treat nasal congestion caused by acute or chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, epistaxis, and hay fever. It is also utilized as a nasal decongestant in the treatment of otitis media.
Pharmacology
Oxymetazoline Hydrochloride is a sympathomimetic amine that is an imidazoline derivative. It acts as a direct agonist on -adrenoceptors but has no effect on -adrenoceptors. When applied topically to the nasal mucosa, it causes a fast and long-acting vasoconstriction of the arterioles, lowering blood flow and decreasing mucosal edema. This improves the potency of the airway and the drainage of the nasal sinuses.
Dosage
Oxymetazoline nasal spray-
Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
Elderly: There is no need for dosage reduction in the elderly for nasal administration.
Children below 6 years of age: It is not suitable for children below 6 years of age.
Oxymetazoline nasal drop-
Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening
Administration
How to use the Nasal Spray-
Shake the bottle gently and remove the dust cover.
Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
Gently blow the nose to clear the nostrils.
Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar of nasal applicator firmly down once to release a spray.
Breathe out through your mouth.
Repeat the above steps in the same/ other nostril for consecutive doses.
Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-
Remove the dust cover.
Gently pull off the nasal applicator.
Wash the applicator and dust cover in warm water.
Shake off the excess water and leave to dry in a normal place. Avoid to apply additional heat.
Gently push the applicator back on the top of the bottle and re-fix the dust cover.
Interaction
Patients using MAO inhibitors or within 14 days of discontinuing such treatment should not be administered Oxymetazoline Hydrochloride Nasal preparation.
Contraindications
It is not recommended for people who have cardiovascular illness, hyperthyroidism, prostatic enlargement, angle closure glaucoma, or are allergic to any of its components.
Side Effects
It may cause local irritation and dryness of the mouth and throat on rare occasions. It is possible to have temporary pain such as burning, stinging, sneezing, or an increase in nasal discharge.
Pregnancy & Lactation
The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and breastfeeding has not been proven, although it is not considered a risk during those times.
Precautions & Warnings
Keep your hands away from your eyes. Without medical guidance, the spray should not be used for more than seven days. Nasal congestion may reoccur or worsen if used often or for an extended period of time.
Storage Conditions
Keep below 30° C in a dry location and away from light. Do not store in the refrigerator or freezer. Keep out of children's reach.
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accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
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and discuss all your queries related to any disease or medicine. We
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