Brigatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer.
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Bigatab 90mg Tablet is used to treat a specific type of non-small cell lung cancer (NSCLC) that has metastasized to other parts of the body. It belongs to a class of medications called kinase inhibitors, working by blocking the action of an abnormal protein that signals cancer cells to multiply, thus slowing or halting the spread of cancer cells.
Before taking Brigatinib, inform your healthcare provider about:
Report any severe or unusual symptoms to your doctor promptly. Serious side effects should be reported to the FDA's MedWatch Adverse Event Reporting program.
Non-Small Cell Lung Cancer
It acts by inhibiting ALK phosphorylation and the activation of downstream signaling proteins.7
Bigatab is indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic Non-Small Cell Lung Cancer (NSCLC) who have progressed on or are intolerant to Crizotinib.
Absorption:
Distribution:
Elimination:
Metabolism:
Excretion:
Drugs that may Increase Bigatab Plasma Concentrations:
Drugs that may Decrease Bigatab Plasma Concentrations:
Drugs that may have their Plasma Concentrations altered by Bigatab:
Hypersensitivity to Brigatinib or any other components.
Interstitial Lung Disease (ILD)/Pneumonitis:
Hypertension:
Bradycardia:
Visual Disturbance:
CPK Elevation:
Pancreatic Enzyme Elevation:
Hyperglycemia:
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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