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Colitrol Plus 1200mg+0.25mcg Tablet
Colitrol Plus Tablet is primarily used to prevent or treat low calcium levels in individuals who do not obtain sufficient calcium from their diet. It is effective in treating conditions caused by calcium deficiency, such as osteoporosis (bone loss), osteomalacia (softening of bones), rickets (abnormal bone growth), hypoparathyroidism (low parathyroid hormone), and latent tetany (muscle spasms). Additionally, it is used in specific patients, such as postmenopausal women, to ensure they are receiving enough calcium.
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✅ Description:
Calcium is essential for the proper functioning of muscles, nerves, cells, and bones. If calcium levels are low, the body will extract calcium from the bones, weakening them. Maintaining the correct amount of calcium is crucial for building and maintaining strong bones. Calcium citrate is easily absorbed, even on an empty stomach, and does not cause constipation, unlike other forms of calcium. It is also less dependent on stomach acid for absorption.
Calcitriol is the active form of Vitamin D3 that promotes the absorption of calcium and phosphate in the intestines. It plays a key role in bone mineralization and helps to regulate calcium levels in the body. In patients with chronic renal failure, calcitriol supplementation compensates for decreased production, improving calcium and phosphate absorption, which can help reverse bone disease symptoms.
In post-menopausal women with osteoporosis, Calcitriol helps increase calcium absorption, elevates circulating levels of calcitriol, and reduces the frequency of vertebral fractures.
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✔️ Common side effects include:
- Constipation
- Nausea
- Abdominal pain
- Hypercalcemia
- Hypercalciuria
- Headache
- Muscle weakness
✔️ Composition: Each tablet contains:
- Calcium Citrate USP: 1200 mg (equivalent to Calcium 252 mg)
- Calcitriol EP: 0.25 mcg
✔️ Dosage & Administration:
Take 1-4 tablets daily, with or without food, as directed by your healthcare provider.
✔️ Interactions:
- Calcium can reduce the absorption of tetracyclines, quinolones, and oral biphosphates.
- Calcium absorption may be decreased by corticosteroids.
- Thiazide diuretics may increase the risk of hypercalcemia and metabolic alkalosis.
- High blood calcium levels can enhance the effects of cardiac glycosides.
- Calcium may reduce the effectiveness of erlotinib.
- Increased risk of hypercalcemia when taken with paricalcitol.
- Enzyme-inducing antiepileptics can accelerate the metabolism of Vitamin D.
- Concurrent use of calcium citrate and aluminum-containing products can lead to fatal encephalopathy in renal failure patients.
✔️ Colitrol Plus is contraindicated in patients with:
- Hypercalcemia (high calcium levels)
- Hypercalciuria (excess calcium in urine)
- Hypophosphatemia (low phosphate levels)
✔️ Pregnancy & Lactation:
Category C. Use as prescribed by your healthcare provider during pregnancy and breastfeeding.
✔️ Use caution in patients with:
- Hypercalcemia
- Malabsorption syndrome
- Heart disease
- Kidney disease or kidney stones
- Sarcoidosis (immune system disorder)
- Liver disease
- Crohn's disease or other bowel disorders
✔️ Storage:
Store in a cool, dry place below 25°C, away from light and moisture. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
