Cholecalciferol [Vitamin D3] 20000 IU is used to treat Osteoporosis
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
Vitamin D3 deficiency can occur in individuals with limited sun exposure or inadequate dietary intake. Vitamin D3 is crucial for the absorption of calcium and phosphate, essential for healthy bones and teeth, and for preventing conditions such as rickets, osteomalacia, and osteoporosis. It is also vital during pregnancy and breastfeeding to prevent pre-eclampsia and support infant growth. Additionally, Vitamin D3 plays a key role in boosting immunity.
While generally safe, side effects may include:
Vitamin D3 is a fat-soluble sterol essential for the regulation of calcium and phosphate homeostasis and bone mineralization. It enhances calcium absorption from the gastrointestinal tract and stimulates bone formation.
The active form of Vitamin D3, Calcitriol, binds to Vitamin D receptors (VDRs) in various body tissues. Vitamin D3, being fat-soluble, has a half-life of around 50 days. It is absorbed in the small intestine, transported to the liver, and metabolized to 25-hydroxy Vitamin D3 (Calcidiol). Further hydroxylation occurs in the kidney, forming 1,25-dihydroxy Vitamin D3 (Calcitriol), which facilitates calcium absorption. Non-metabolized Vitamin D3 is stored in fat and muscle tissues and is excreted via feces and urine.
- Nutritional Deficiency: Oral/IM: 5-10 mcg or 1-2 ml (200-400 IU) daily.
- Osteoporosis Prophylaxis and Treatment (Age >50): 800-1000 IU (20-25 mcg) orally daily with calcium supplements. May also be administered via IM injection.
- Hypoparathyroidism: 50,000-200,000 IU (0.625-5 mg) orally daily with calcium supplements. May also be administered via IM injection.
Nutritional Supplementation:
- 0-12 months: 400 IU (10 mcg) orally daily.
- 1-18 years: 600 IU (15 mcg) orally daily.
- Vitamin D-Resistant Rickets: 12,000-500,000 IU (0.3-12.5 mg) orally daily.
- Familial Hypophosphatemia: 40,000-80,000 IU (1-2 mg) orally daily with phosphate supplements; dosage may be reduced after the growth phase is complete.
Colecalciferol is contraindicated in conditions associated with hypercalcemia and in patients with known hypersensitivity to Colecalciferol or its excipients. It is also contraindicated in cases of vitamin D toxicity.
Doses up to 4,000 IU are considered safe during pregnancy. The recommended daily intake for pregnant women is 400 IU, though higher doses may be needed for those deficient in Vitamin D3. Pregnant women should follow medical advice specific to their condition.
Vitamin D3 and its metabolites are excreted in breast milk, but no overdosing effects in infants have been observed. When prescribing additional Vitamin D3 to a breastfed child, the mother's dose should be considered.
Exercise caution when considering vitamin D supplements in individuals with:
Vitamin D should be taken with adequate calcium and magnesium. During lactation, vitamin D is distributed into breast milk; use with caution.
Store below 30°C, protected from light and moisture. Keep out of reach of children
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.