Zoledronic acid is used in the treatment of osteoporosis. It treats osteoporosis in postmenopausal women and men at high risk of fractures.
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Zometa (zoledronic acid) is indicated for the following conditions:
The interaction of alcohol with Zoledronic Acid is currently unknown. It's advisable to consult a doctor before consuming alcohol while taking Zoledronic Acid to ensure safety and minimize any potential risks.
Zoledronic Acid is categorized as a pregnancy category D drug, meaning it's not recommended for pregnant women as it may harm the unborn baby. Consult your doctor if you are pregnant.
Breastfeeding mothers should avoid Zoledronic Acid as it is contraindicated during breastfeeding. Consult a doctor for guidance.
Zoledronic Acid may cause dizziness, so it's important to avoid driving or operating machinery if you experience dizziness after taking the medication.
If you have a history of kidney diseases/conditions, take Zoledronic Acid with caution. Your doctor may adjust the dose accordingly. Avoid Zoledronic Acid if you have severe kidney problems.
If you have a history of kidney diseases/conditions, take Zoledronic Acid with caution. Your doctor may adjust the dose accordingly. Avoid Zoledronic Acid if you have severe kidney problems.
Zoledronic Acid contains Zoledronic acid, which binds tightly to bones and inhibits the action of osteoclasts, cells responsible for breaking down bone tissue. By preventing bone breakdown, Zoledronic Acid helps maintain bone strength.
Common side effects may include headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, muscle or joint pain, swelling, or pain at the infusion site. Most side effects are temporary and do not require medical intervention.
Zoledronic Acid is used to treat various conditions including:
Zoledronic acid acts mainly on bones as an inhibitor of osteoclast-mediated bone resorption. It targets mineralized bone and rapidly distributes to bones when administered intravenously. It primarily inhibits farnesyl pyrophosphate synthase in osteoclasts, reducing bone resorption. Additionally, it exhibits antitumor, antiangiogenic, anti-pain, cytostatic, and pro-apoptotic activities on tumor cells.
The recommended doses vary based on the condition being treated:
Zoledronic Acid should be diluted with a calcium-free infusion solution before administration. Infusion should last at least 15 minutes. The solution should be used promptly or stored at refrigerated temperatures for up to 24 hours.
Hypersensitivity to the drug, severe renal impairment, pregnancy, and breastfeeding are contraindications for Zoledronic Acid.
Zoledronic Acid is not recommended for pregnant or breastfeeding women.
Store below 30°C, protected from moisture and light, and out of reach of children.
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