Generic Name: Halobetasol Propionate 0.05% Topical
Manufacturer: Incepta Pharmaceuticals Ltd.
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Ulticort belongs to a group of medicine called steroids. It is used for treatment of allergic disorders and inflammatory skin conditions. It provides relief from swelling, redness, and itching in the affected area. Ulticort is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine evenly on the affected skin. Use it regularly to get the maximum from it. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water in case of accidental contact. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor. Using of the medicine may cause stinging, burning, or itching at the site of application. These side effects are temporary and usually go away with time. However, if they persist or worsen, let your doctor know. Pregnant and breastfeeding mothers should consult their doctors before using this medicine. It is not recommended for children under 12 years of age.
Uses of Ulticort
Side effects of Ulticort
Common
How to use Ulticort
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Ulticort works
Ulticort is a steroid. It works by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.
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Brief Description
Indication
Psoriasis, Eczema, Corticosteroid-responsive dermatoses
Administration
A thin layer should be applied to the affected skin once or twice daily and rub in gently and completely.
Adult Dose
Inflammatory, Pruritic & Steroid-Responsive Dermatoses Apply topically to affected area(s) BID Not to exceed 50 g/week; do not use longer than 2 consecutive weeks
Child Dose
Inflammatory, Pruritic & Steroid-Responsive Dermatoses <12 years: Safety and efficacy not established >12 years: Apply topically to affected area(s) BID Not to exceed 50 g/wk; do not use longer than 2 wk
Contraindication
Halobetasol Propionate Cream/Ointment is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Mode of Action
Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.
Precaution
Systemic absorption of topical corticosteroids may cause reversible hypothalamic-pituitaryadrenal (HPA) axis suppression, manifestations of cushing\'s syndrome, hyperglycemia, and glucosuria. Patients receiving large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Lactation: excretion of topical corticosteroids in breast milk is unknown; use with caution
Side Effect
Skin atrophy,Striae,Acneform lesions,Intracranial hypertension,Allergic contact dermatitis,Pruritus,Pustulation,Perioral dermatitis,Urticaria,Hypertrichosis,Leukoderma,Pigmentation changes,HPA suppression (with higher potency used >2 wk)
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