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Nictoris 10mg 14pcs Tablet
Nictoris is prescribed for the prevention and long-term treatment of angina pectoris.
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✅ Description:
Nicorandil, Vasodilators, Prevention, and treatment of angina pectoris in adults who cannot take beta-blockers.
Nicorandil contains Nicorandil, a potassium-channel activator. It:
- Opens potassium channels in the muscle cells of blood vessels.
- Relaxes and widens these blood vessels.
- Reduces the heart's workload by making it easier to pump blood.
- Increases oxygen and blood supply to the heart muscle by widening coronary arteries.
Take as prescribed by your doctor. Continue for as long as your doctor advises based on your medical condition.
- Inform your doctor if you are allergic to Nicorandil or any other medicines.
- Inform your doctor if you are allergic to Nicorandil or any other medicines.
- Not recommended for children; safety and effectiveness not established.
Safety Advices
Alcohol
UNSAFE
It is unsafe to consume alcohol with Nictoris 10.
Pregnancy
CONSULT YOUR DOCTOR
Nictoris 10 may be unsafe during pregnancy. Limited human studies suggest potential risks. Consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Consult your doctor regarding the use of Nictoris 10 during breastfeeding, as information is not available.
Driving
CAUTION
Nictoris 10 may decrease alertness, affect vision, or cause drowsiness and dizziness. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
Nictoris 10 is probably safe for patients with kidney disease. Limited data suggest dose adjustment may not be needed but consult your doctor.
Liver
CONSULT YOUR DOCTOR
Nictoris 10 is probably safe for patients with liver disease. Limited data suggest dose adjustment may not be needed but consult your doctor.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Nicorandil
Angina pectoris (heart-related chest pain)
✔️ How does Nicorandil work?
Nicorandil works by dilating arterioles and large coronary arteries through the opening of potassium channels and stimulating guanylate cyclase, leading to venous vasodilation. This action reduces preload and afterload, enhancing coronary blood flow.
✔️ Side Effects of Nicorandil
Common side effects include headache (usually temporary), flushing, dizziness, nausea, vomiting, and weakness. High doses can cause hypotension and reflex tachycardia.
✔️ Quick Suggestions:
- Follow a cholesterol-lowering diet.
- Consume low-salt and a low-fat diet.
- Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
- Limit salt and sugar intake.
- Avoid smoking and alcohol consumption.
- Choose healthy fats and cut down on trans fats.
- Include omega-3 fatty acids, fiber-rich food, fruits and vegetables.
- Get active by doing any physical activity such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.
- Regular exercise is recommended along with Nicorandil for effective results.
✔️ Indication of Nicorandil
Nictoris 10 is indicated for the prevention and long-term treatment of angina pectoris.
✔️ Pharmacology
Nicorandil, the active ingredient in Nictoris, works by dilating arterioles and large coronary arteries through the opening of potassium channels. It also stimulates guanylate cyclase, leading to venous vasodilation. This action reduces both preload and afterload, improving coronary blood flow.
✔️ Dosage & Administration of Nicorandil
- Adults: The standard dose range is 10 to 20 mg twice daily. The starting dose is typically 10 mg twice daily, taken in the morning and evening, and may be increased based on the patient's needs, response, and tolerance, up to 40 mg twice daily. For patients prone to headaches, a lower starting dose of 5 mg twice daily may be used.
- Elderly: Use the lowest effective dose, administered with caution.
- Children: Not recommended.
- Hepatic Impairment: Dose adjustment may be required.
✔️ Interaction
While studies have shown no significant interactions with beta-blockers, calcium antagonists, digoxin, a digoxin/furosemide combination, rifampicin, or cimetidine, Nicorandil might still enhance the effects of other vasodilators, tricyclic antidepressants, and antihypertensive drugs, especially when combined with alcohol.
✔️ Contraindications
- Hypersensitivity to Nicorandil
- Cardiogenic shock
- Acute myocardial infarction with acute left ventricular failure and low filling pressures
- Hypotension
- Concurrent use with phosphodiesterase-5 inhibitors, due to the risk of severe hypotension
✔️ Pregnancy & Lactation
- Pregnancy: Animal studies show no harm to the fetus, but human studies are lacking. Use only if the potential benefits outweigh the risks.
- Lactation: Unknown if Nicorandil is excreted in human milk. Use caution when administering to nursing mothers.
✔️ Precautions & Warnings
- Use cautiously in patients with blood volume depletion or low systolic blood pressure (below 100 mm Hg).
- Avoid use in patients with cardiogenic shock or acute myocardial infarction with acute left ventricular failure and low filling pressures.
- Discontinue use if mouth ulceration, stomatitis, or severe buccal ulcerations occur.
- Use with caution in patients with glaucoma.
- Nicorandil can enhance the hypotensive effects of other vasodilators, tricyclic antidepressants, and alcohol.
- In hypertensive patients, monitor blood pressure closely when combined with antihypertensive medications.
✔️ Storage Conditions:
Store in a cool, dry place, protected from light.
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