Solivo 500mg | 500mg + 20mg | View Price, Uses, Side Effects | ePharma
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Solivo 500mg Tablet

Generic: Naproxen + Esomeprazole

Type: Tablet

Pack Size: 6 Pcs

Solivo 500mg Tablet is used to relieve pain in the following conditions:

  • Muscles, joints, and tendons problems such as strains, gout, ankylosing spondylitis (pain and stiffness in the neck and back), or arthritis
  • Painful heavy periods and bleeding due to insertion of an intrauterine device (women)
  • Migraine headache
  • Rheumatoid arthritis (children)

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Discount Price: ৳ 84.6
MRP: ৳ 90 6% Off

⪼ Save  ৳: 5.4  in this Product


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✅ Description:

  • Solivo 500mg Tablet is used to relieve pain associated with various conditions, including muscle, joint, and tendon problems such as strains, gout, ankylosing spondylitis (neck and back pain/stiffness), migraine headache, arthritis, painful heavy periods, bleeding due to intrauterine device insertion, and rheumatoid arthritis in children.
  • This medication should be used with caution in patients who have a history of asthma, allergies (hay fever), swelling of the face, lips, eyes, or tongue, liver or kidney problems, blood vessel problems, clotting disorders, localized swelling, high blood pressure, heart failure, previous stroke or heart conditions, or those at risk of these conditions.
  • Solivo 500mg Tablet is not recommended for patients with serious liver or kidney problems, or heart failure. It is important to consult a doctor for advice if you have these conditions.
  • Solivo 500mg Tablet is generally not recommended for use in pregnant women during the last three months of pregnancy, as it may harm the baby. It is also not recommended for use in breastfeeding women. Consult your doctor for advice in these situations.
  • Solivo 500mg Tablet should be used with caution in children over 5 years of age and in elderly patients. It is advisable to consult a doctor before giving this medication to children or elderly individuals.
  • Solivo 500mg Tablet exactly as directed by your healthcare provider. Do not increase the dose without consulting the prescriber. It is recommended to take the medication with food or milk to reduce gastrointestinal distress. Adequate fluid intake should be maintained unless instructed otherwise.

Please note that the information provided here is based on the salt content of the medicine, and the specific uses and effects may vary from person to person. It is always advisable to consult a healthcare professional, such as an orthopedic specialist or a doctor, before using this medicine to ensure it is suitable for your specific condition and to receive proper guidance.

Safety Advices


Alcohol
UNSAFE

Taking this medication with alcohol can increase the risk of stomach bleeding caused by naproxen.


Pregnancy
UNSAFE

Solivo 500mg Tablet is not recommended for use during pregnancy, especially in the third trimester, as it may cause harm to your developing fetus. Hence consult your doctor before taking this medicine if you are pregnant. 


Breastfeeding
UNSAFE

Solivo 500mg Tablet may pass into the breastmilk in small amounts. Hence if you are breastfeeding, consult your doctor to understand the potential risks and benefits before taking this medicine.


Driving
CAUTION

Solivo 500mg Tablet may cause side effects that could affect your ability to drive. Solivo 500mg Tablet may make you feel dizzy, depressed, sleepy, and tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.


Kidney
CAUTION

This medicine should not be given for renal failure. Caution should be used in patients with severe renal impairment.


Liver
CAUTION

Solivo 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Solivo 500mg Tablet may be needed. Please consult your doctor.

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✔️ Uses of Solivo 500mg Tablet
  • Rheumatoid Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis
  • Dysmenorrhea
  • Gout
  • Swelling and pain
✔️ How does Solivo 500mg Tablet

Solivo 500mg Tablet is a combination medication that contains two active ingredients: Naproxen and Esomeprazole. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that helps reduce pain, fever, and inflammation by blocking the production of certain chemicals called prostaglandins in the body. These prostaglandins are responsible for triggering pain and inflammation.

However, NSAIDs like Naproxen can sometimes cause irritation and damage to the stomach lining, leading to conditions like gastritis or ulcers. To counteract this potential side effect, Esomeprazole, a proton-pump inhibitor (PPI), is included in the combination medication. Esomeprazole reduces the amount of acid produced in the stomach, thereby helping to prevent stomach ulcers and protect the stomach lining from the potential harm caused by Naproxen.

The combination of Naproxen and Esomeprazole is often prescribed for individuals who require pain relief while minimizing the risk of stomach irritation or ulcers associated with NSAIDs. 

✔️ Side Effects of Solivo 500mg Tablet
  • Heartburn and dyspepsia (indigestion): These symptoms are often related to acid reflux, where stomach acid flows back into the esophagus, causing a burning sensation in the chest or upper abdomen.
  • Nausea: Nausea is a feeling of queasiness or an urge to vomit. It can be caused by various factors, including gastrointestinal issues, infections, motion sickness, pregnancy, or certain medications.
  • Sore mouth or mouth ulcers: Mouth sores or ulcers can occur due to various reasons, such as viral or bacterial infections, trauma, autoimmune conditions, or vitamin deficiencies.
  • Abdominal pain: Abdominal pain can have numerous causes, including digestive issues (such as gastritis or irritable bowel syndrome), infections, inflammation, organ problems, or muscle strain.
  • Constipation: Constipation refers to difficulty or infrequent bowel movements. It can occur due to inadequate fiber intake, dehydration, lack of physical activity, certain medications, or underlying medical conditions.
  • Headache, dizziness: Headaches and dizziness can have multiple causes, ranging from tension headaches and migraines to inner ear disorders, low blood sugar, dehydration, or even stress.
  • Fits or seizures: Seizures are caused by abnormal electrical activity in the brain and can result in uncontrolled movements, altered consciousness, and other symptoms. Seizures can be associated with epilepsy, brain injuries, infections, or other neurological conditions.
  • Bruising, itching, sweating, skin sensitivity, or hair loss: These symptoms can be related to various dermatological conditions, allergic reactions, autoimmune disorders, or side effects of medications.
  • Changes in eyesight (eye pain): Eye pain and changes in vision can be caused by eye strain, dry eyes, infections, allergies, or more serious conditions like glaucoma or cataracts.
  • Hearing loss and ringing in the ears: Hearing loss and tinnitus (ringing in the ears) can occur due to exposure to loud noises, aging, ear infections, certain medications, or underlying ear disorders.
  • A fluttering feeling in the heart: A fluttering sensation in the heart can be a symptom of palpitations, which may be caused by irregular heart rhythms (arrhythmias), anxiety, caffeine, medications, or other factors.
  • Thirst, fever, feeling tired, or generally unwell: These symptoms can occur in various illnesses, including infections, inflammatory conditions, or systemic disorders.
  • Swelling of hands, feet, or legs: Swelling, also known as edema, can be a result of fluid retention and may be associated with conditions such as heart failure, kidney problems, liver disease, or certain medications.
  • Difficulty breathing, including shortness of breath, wheezing, or coughing: These respiratory symptoms can be caused by asthma, chronic obstructive pulmonary disease (COPD), allergies, respiratory infections, or other lung conditions.
  • Kidney problems: Kidney problems can manifest with symptoms like changes in urination patterns, fluid retention, fatigue, or discomfort in the kidney area.
  • Vomiting: Vomiting can occur due to various reasons, including infections, gastrointestinal disorders, food poisoning, medications, or underlying medical conditions.
  • Skin rashes: Skin rashes can have numerous causes, such as allergic reactions, infections, autoimmune diseases, contact with irritants, or certain medications.
✔️ Quick Suggestions:
  • Solivo 500mg Tablet is used to treat various painful conditions.
  • Take it with a glass of milk in order to prevent side effects such as indigestion.
  • If you have asthma, symptoms such as wheezing or breathlessness might get worse Solivo 500mg Tablet. In such a case see your doctor right away.
  • Inform your doctor if you have or ever had ulcers in your stomach or intestines.
  • Inform your doctor if you are planning to have an operation (even a minor one, such as tooth extraction) since Solivo 500mg Tablet increases the risk of bleeding.
✔️ Indication of Solivo 500mg Tablet

Naproxen + Esomeprazole is used for pain relief.

✔️ Pharmacology

The combination Tablet Solivo 500 comprises an outer layer of prompt-release Esomeprazole Magnesium and an inner layer of enteric-coated Naproxen. This design ensures that Esomeprazole is released first in the stomach before the Naproxen is dissolved in the small intestine.

Naproxen is a non-steroidal anti-inflammatory drug (NSAID) with analgesic (pain-relieving) and antipyretic (fever-reducing) properties. It works by inhibiting the synthesis of prostaglandins, which are chemicals involved in pain and inflammation.

Esomeprazole is a proton pump inhibitor (PPI) that reduces gastric acid secretion. It specifically inhibits the H+/K+-ATPase enzyme in the gastric parietal cells, which are responsible for producing stomach acid. By targeting the proton pump, Esomeprazole blocks the final step in acid production, resulting in a decrease in gastric acid secretion.

The combination of Esomeprazole and Naproxen in this tablet aims to provide pain relief while also reducing the risk of gastric ulcers and other gastrointestinal side effects associated with Naproxen use. The Esomeprazole component helps protect the stomach lining by reducing the acidity in the stomach.

✔️ Dosage & Administration of Solivo 500mg Tablet

It is important to carefully consider the potential benefits and risks of using Solivo 500mg Tablet, as well as other treatment options, before making a decision. Here are some key points to consider:

Dosage: The recommended dosage of Solivo 500mg Tablet for different conditions is as follows:

  • Rheumatoid Arthritis, Osteoarthritis, and Ankylosing Spondylitis in adults: One tablet twice daily containing either 375 mg naproxen/20 mg esomeprazole or 500 mg naproxen/20 mg esomeprazole.
  • Juvenile Idiopathic Arthritis in patients 12 years of age and older:
    • Weight greater than 50 kg: One tablet twice daily containing either 375 mg naproxen/20 mg esomeprazole or 500 mg naproxen/20 mg esomeprazole.
    • Weight 38 kg to less than 50 kg: One tablet twice daily containing 375 mg naproxen/20 mg esomeprazole.

Individualized treatment: The dosage and duration of treatment should be determined by your physician based on your age, body weight, and the specific disease condition being treated. It's important to follow your doctor's instructions regarding the correct dose and duration of treatment.

Swallowing instructions: Take Solivo 500mg Tablet as advised by your physician. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet, as it is designed to be swallowed intact.

Individual considerations: Each person's response to medication can vary, and it's essential to discuss your medical history, including any allergies, asthma, liver or kidney problems, or other underlying conditions, with your doctor. This information will help your physician determine if Solivo 500mg Tablet is appropriate for you or if an alternative treatment should be considered.

Always consult your physician for personalized advice regarding the use of Solivo 500mg Tablet. They will evaluate your specific circumstances and provide the most suitable treatment plan for you.

✔️ Interaction

When taking multiple medications, there is a risk of drug interactions, as well as interactions with certain foods and beverages. Here are some specific points regarding Solivo 500mg Tablet:

Interaction with Alcohol: It is advised to avoid alcohol consumption while taking this medication, as it can increase the risk of stomach bleeding.

Interaction with Other Drugs:

  • Increased toxicity: Naproxen may displace other highly protein-bound drugs, such as oral anticoagulants, hydantoins, salicylates, sulfonamides, and sulfonylureas, leading to increased levels of those drugs in the blood.
  • Naproxen and Warfarin: Concurrent use of Naproxen and Warfarin may cause a slight increase in free Warfarin levels, which could potentially increase the risk of bleeding.
  • Naproxen and probenecid: Concurrent use of Naproxen and probenecid may increase the plasma half-life of naproxen.
  • Naproxen and methotrexate: Concurrent use of Naproxen and methotrexate may significantly increase and prolong blood methotrexate concentration, which can be severe or fatal. Close monitoring is necessary in such cases.

Interaction with Diseases:

  • GI disease: Use Solivo 500mg Tablet with caution in patients with a history of GI bleeding or ulcers.
  • Cardiovascular disease: Use caution in patients with congestive heart failure (CHF) and hypertension.
  • Dehydration: Naproxen should be used with caution in patients who are dehydrated.
  • Renal or hepatic impairment: Patients with kidney or liver problems should use Naproxen with caution.
  • Anticoagulants: Patients receiving anticoagulant therapy should be monitored closely when taking Naproxen.
  • Ophthalmologic evaluation: For patients who develop eye complaints (such as blurred vision, diminished vision, changes in color vision, or retinal changes) during Naproxen therapy, an ophthalmologic evaluation should be performed.
  • Photosensitivity: Naproxen has been associated with photosensitivity reactions.

Interaction with Food: Food may decrease the rate but not the extent of oral absorption of Solivo 500mg Tablet. To minimize gastrointestinal upset, it is recommended to take Naproxen with food or milk.

It is important to discuss your specific medical history, including any other medications, diseases, or dietary considerations, with your healthcare provider to ensure the safe and effective use of Solivo 500mg Tablet. They can provide personalized advice and guidance based on your individual circumstances.

✔️ Contraindications

If you have any of the following conditions or history, it is important to avoid the use of Solivo 500mg Tablet:

  • Known hypersensitivity: If you have a known hypersensitivity or allergy to any component of the tablet or substituted benzimidazoles, it is advised not to use Solivo 500mg Tablet.
  • History of asthma, urticaria, or allergic-type reactions to NSAIDs: If you have a history of asthma, urticaria (hives), or other allergic-type responses after taking ibuprofen or other NSAIDs, it is recommended to avoid Solivo 500mg Tablet due to the risk of potential allergic reactions.
  • The peri-operative period in the setting of coronary artery bypass graft (CABG) surgery: Solivo 500mg Tablet should not be used during the peri-operative period in the context of CABG surgery. This is because NSAIDs, including Naproxen, may increase the risk of cardiovascular events and hinder the healing process after surgery.
  • History of stomach or duodenal ulcers or bleeding: If you currently have an ulcer or bleeding from the stomach or duodenum or have had these conditions in the past, it is not recommended to use Solivo 500mg Tablet. NSAIDs, including Naproxen, can worsen these conditions and increase the risk of gastrointestinal bleeding.
  • History of bleeding in the stomach or intestines while taking NSAIDs: If you have a history of bleeding in the stomach or intestines while taking NSAIDs, it is important to avoid Solivo 500mg Tablet. Using NSAIDs in such cases can increase the risk of recurrent bleeding.

If you have any of these conditions or a history related to the use of Solivo 500mg Tablet, it is crucial to inform your healthcare provider. They will be able to recommend alternative treatment options that are more suitable for your situation.

✔️ Pregnancy & Lactation

Pregnancy category C. In late pregnancy, it ought to be dodged since it may cause untimely closure of the ductus arteriosus. This tablet ought to not be utilized in nursing moms due to the Naproxen component.

✔️ Precautions & Warnings
  • Patients with known CV disease or risk factors may be at a higher risk when using this tablet. It is important to use Solivo 500mg Tablet with caution in such patients and to discuss the potential risks and benefits with your doctor.
  • Patients with fluid retention or heart failure should use Solivo 500mg Tablet with caution, as it may exacerbate these conditions. Inform your doctor if you have any symptoms or a history of fluid retention or heart failure.
  • If you have an autoimmune condition, it is important to inform your doctor before taking Solivo 500mg Tablet. The use of NSAIDs, including Naproxen, may affect the immune system and could potentially worsen autoimmune conditions.
  • Patients with colitis or Crohn's disease should use Solivo 500mg Tablet with caution, as it may worsen these conditions. Inform your doctor if you have a history of colitis or Crohn's disease.
  • If you experience a feeling of weakness while taking Solivo 500mg Tablet, it is important to inform your doctor. This could be a potential side effect that needs to be evaluated.
  • If you have lumps in the nose, sneezing, or any nasal symptoms such as a runny, blocked, or itchy nose (rhinitis), it is important to inform your doctor before using Solivo 500mg Tablet.
  • If you are on a low-salt diet and have had previous digestive problems, it is important to inform your doctor before using Solivo 500mg Tablet Certain gastrointestinal conditions may require additional caution and monitoring when using this medication.
  • Pediatrics: Solivo 500mg Tablet is not recommended for use in children below 5 years of age. Consult your doctor for suitable alternatives and guidance.
  • Geriatrics: Solivo 500mg Tablet should be used with caution in elderly patients. It is advisable to consult your doctor before taking this medicine, as older individuals may be more susceptible to the side effects and risks associated with this medication.
✔️ Storage Conditions

Store at a temperature of underneath 30°C, secure from light & dampness. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Solivo 500mg Tablet may show its action within one hour.

Solivo 500mg Tablet may remain effective in the body for approximately 8-12 hours.

No

This medication is to be taken till the time you see an improvement in your health conditions.

Solivo 500mg Tablet has not been reported to have any addictive potential.

If you miss a dose of Solivo 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take double the dose.

Naproxen: A Medicine to treat pain and swelling
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Check our pricing section for Solivo 500mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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