Trimetazidine Dihydrochloride 20 mg Tablet is used to treat ischemic heart disease, angina pectoris, and complications arising from infarction
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Trimet 20mg Tablet, containing Trimetazidine, falls under the category of Anti-anginal agents. This medication is intended for adult patients grappling with angina pectoris—a chest pain arising from heart disease. It shields heart cells from the repercussions of reduced oxygen supply during angina episodes.
Angina pectoris emerges as a consequence of decreased blood flow to the heart. It serves as a symptom of an underlying coronary heart disease characterized by the narrowing or blockage of blood vessels that transport blood and oxygen to the heart. The onset of angina often entails abrupt, intense chest pain, pressure, or discomfort that can radiate to the left shoulder. This distress can also manifest in the jaw, neck, back, or abdomen. Some individuals might encounter shortness of breath or fatigue.
It's vital to note that Trimet 20mg Tablet is not advised for individuals afflicted with Parkinson's disease or severe kidney issues.
This medication requires cautious use among elderly patients (above 75 years), pregnant women, and breastfeeding mothers. If you experience dizziness after consuming Trimet 20mg Tablet, avoid operating machinery or driving.
Common side effects associated with Trimet 20mg Tablet encompass dizziness, headache, abdominal pain, diarrhea, vomiting, indigestion, nausea, rashes, itching, hives, and a sensation of weakness. Consult your doctor if these conditions endure or worsen.
Refrain from alcohol consumption while on Trimet 20mg Tablet to avoid heightened dizziness.
Usage of Trimet 20mg Tablet during pregnancy should only occur if explicitly necessary. Consult your doctor before proceeding.
Breastfeeding women are advised to avoid Trimet 20mg Tablet. Seek guidance from your doctor prior to consumption.
Abstain from driving or operating machinery if you experience dizziness after ingesting Trimet 20mg Tablet.
Avoid Trimet 20mg Tablet if you have kidney-related issues. Seek your doctor's counsel beforehand.
Trimet 20mg Tablet is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Trimet 20mg Tablet functions by optimizing the metabolism of fatty acids and glucose, thereby augmenting blood flow and oxygen supply to the heart. It also diminishes the thickening and scarring of heart tissue. This combined effect leads to the reduction of chest pain due to blood vessel narrowing or blockage.
Common
Rare
In case you experience any of the following signs, immediately cease Trimet 20mg Usage and consult your doctor:
Trimet 20mg Tablet contains the active ingredient Trimetazidine, which functions as a 'metabolic agent.' This compound impacts metabolism, which is the process of breaking down substances in the body. By altering metabolism, Trimet 20mg Tablet reduces the body's demand for oxygen by transitioning the metabolic process from utilizing fats to utilizing glucose. This adjustment results in an improved efficiency of the heart's function and a decreased requirement for oxygen.
Furthermore, besides its role in treating angina and improving cardiac efficiency, Trimetazidine is also utilized in the management of other conditions. It is employed to address vertigo, characterized by a spinning sensation, as well as tinnitus, which involves a ringing sensation in the ears. Additionally, Trimetazidine is used to alleviate issues related to reduced vision and disturbances in the visual field, which can manifest as unclear or disrupted vision.
Trimetazidine Dihydrochloride operates as a metabolic anti-ischemic drug that offers notable benefits for individuals with cardiac concerns. It functions by inhibiting the fatty acid pathway and directing oxygen toward the glucose pathway through the inhibition of the 3-ketoacyl CoA thiolase enzyme—a process facilitated by its action as a 3-ketoacyl CoA thiolase inhibitor (KAT).
This redirection of energy metabolism to the glucose pathway proves to be more efficient. As a result, despite utilizing the same amount of oxygen, more energy is generated, consequently leading to an increased heart rate. Moreover, the oxidation of glucose in an aerobic manner curbs the accumulation of lactic acid, which in turn serves to prevent the occurrence of angina pectoris—an outcome that holds significant therapeutic value for individuals grappling with this condition.
The standard dosage of Trimetazidine is typically 35 mg taken twice daily, or alternatively, a 20 mg tablet can be taken three times daily during meals.
Administer Trimet 20mg Tablet as directed by your physician. Swallow the medicine with water, refraining from crushing or chewing it. Your doctor will determine the appropriate dosage and duration based on factors such as your age, body weight, and medical condition.
Before initiating the Trimet 20mg Tablet, inform your doctor about other medications you are taking, including those acquired without a prescription.
Contraindications include hypersensitivity to the active ingredient or any excipients, and the medicine is not recommended for individuals with Parkinson's disease, Parkinsonian symptoms, tremors, restless legs syndrome, or significant renal impairment.
Regarding pregnancy, there is no available information about Trimetazidine's use in pregnant women. Animal studies suggest no direct or indirect adverse effects on reproduction. However, as a precaution, it is advised to avoid using Trimetazidine during pregnancy. While Trimetazidine is not known to be excreted in human milk, a potential risk to neonates and infants cannot be ruled out. Breastfeeding mothers are advised to avoid taking Trimetazidine.
Do not consume Trimet 20mg Tablet if you:
Keep in a dry place away from light and heat. Keep out of the reach of children.
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