Manufacturer/Distributor: Novartis (Bangladesh) Ltd.
Generic Name: Diclofenac Sodium 12.5 mg Suppository
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Rheumatology includes inflammatory and degenerative rheumatism, polyarthritis, ankylosing spondylarthritis, osteoarthritis, spondylarthroses, acute gout, and peri-articular rheumatic diseases.
Sprains, bruises, dislocations, fractures, soft-tissue injuries, and surgical procedures are all examples of surgery and traumatology.
Primary dysmenorrhoea, episiotomy, adnexitis, endometritis, parametritis, salpingitis, and mastitis are all conditions seen in obstetrics and gynecology.
Pre-operative medication for the prevention of pain, inflammation, and edema in otorhinolaryngology.
Post-operative and post-traumatic discomfort, inflammation, and swelling are common in dentistry.
Dilofenac Sodium is an anti-rheumatic, anti-inflammatory, analgesic, and antipyretic non-steroidal anti-inflammatory medication (NSAID). It also contains uricosuric properties. Diclofenac works by inhibiting prostaglandin production, which is a key factor in the development of inflammation, discomfort, and fever.
When taken with or after a meal, diclofenac is swiftly and thoroughly absorbed from the gastrointestinal tract. After consumption, peak plasma concentrations are obtained in an average of 2 hours. It is 99.7% bound to plasma proteins at therapeutic dosages. Diclofenac is metabolized in the liver and goes through a first-pass process.
Diclofenac FC Tablet: Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food. Dose should be reduced in long term use.
Diclofenac SR Tablet:
Diclofenac Dispersible Tablet:
Diclofenac TR Capsule: One capsule daily. Diclofenac TR should be taken preferably after mealtimes.
Diclofenac Suppository: For adults: 50 mg suppository 2-3 times daily. Maximum daily dose is 150 mg.
Diclofenac injection: For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.
Diclofenac Gel: For external use only. Depending on the size of area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily. To the affected area gel should be rubbed in lightly. This gel may also be given in addition to further treatment with other dosage forms of Diclofenac.
Patients who are hypersensitive to any of the items' ingredients should avoid using it. Peptic ulcer, hypersensitivity to Diclofenac, as well as other non-steroid anti-inflammatory agents. Diclofenac is also contra-indicated in asthmatic patients who have had an attack of asthma, urticaria, or acute rhinitis triggered by acetylsalicylic acid or other drugs that inhibit prostaglandin synthetase.Under occlusive airtight dressings, this Gel should not be utilized.
When taken with or after a meal, diclofenac is swiftly and thoroughly absorbed from the gastrointestinal tract. After consumption, peak plasma concentrations are obtained in an average of 2 hours. It is 99.7% bound to plasma proteins at therapeutic dosages. Diclofenac is metabolized in the liver and goes through a first-pass process.Diclofenac Sodium Gel can produce skin irritation, reddening, and a rash on the affected area.
Diclofenac should only be used if absolutely necessary during pregnancy. The smallest dose that is effective should be utilized. These medications are not advised to be taken during the first trimester of pregnancy. Diclofenac Sodium Gel is not suggested during pregnancy due to a lack of clinical evidence. Diclofenac can be found in extremely small amounts in breast milk, however it has no negative effects.
In rare cases, patients using Diclofenac may develop peptic ulcers or experience gastrointestinal bleeding. Patients in their advanced years should be closely monitored. Diclofenac Sodium Gel should not be applied to the eyes or mucous membranes, and the hands should be thoroughly cleansed after application. It should not be consumed by mouth.
Non-steroidal anti-inflammatory drugs, drugs for osteoarthritis, drugs for rheumatoid arthritis (NSAIDs)
Store in a cold, dry, and light-protected location. Keep it below 30°C. Keep out of children's reach.
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