✔ 100% Authentic Product
👁️ Currently Viewing 474
Tripar 5 Tablet 1 Strip
Tripar (Trihexyphenidyl) is a centrally acting anticholinergic that blocks muscarinic receptors, with preference for the M1 subtype in the brain. It reduces cholinergic activity and may indirectly increase dopamine release in the striatum, improving motor symptoms in Parkinson's disease.
Not recommended due to lack of established safety and efficacy data.
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Cash on Delivery - All over Bangladesh
Regular Delivery - 8-12 Hours, Dhaka City*- Regular Delivery - 24-48 Hours, All Over Bangladesh*
✅ Description:
Tripar is used as an adjunctive therapy in managing all types of Parkinsonism, including idiopathic, arteriosclerotic, and postencephalitic. It is particularly effective when used alongside levodopa. Additionally, it is indicated to relieve extrapyramidal side effects caused by central nervous system medications such as phenothiazines, thioxanthenes, butyrophenones, and dibenzoxazepines.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects & Overdose of Tripar 5
Common: Dry mouth, blurred vision, dizziness, nausea, nervousness.
Serious/Rare: Cognitive impairment, urinary retention, constipation, hallucinations, glaucoma, heat intolerance, paralytic ileus, psychiatric disturbances.
Abrupt discontinuation may cause Parkinsonism rebound or Neuroleptic Malignant Syndrome (NMS).
Overdose
Symptoms: Delirium, hallucinations, dry skin, blurred vision, urinary retention, cardiac issues, seizures, coma.
Management: Supportive care, gastric lavage, diazepam for agitation, avoid phenothiazines, maintain hydration and electrolyte balance.
✔️ Dosage & Administration
- Idiopathic Parkinsonism: Start with 1 mg daily, increasing by 2 mg every 3–5 days up to 6–10 mg/day; up to 12–15 mg may be required in postencephalitic cases.
- Drug-induced Parkinsonism: Typically, 5–15 mg/day in divided doses; start with 1 mg and titrate based on response.
- With Levodopa: Use 3–6 mg/day in divided doses, adjusting both drugs to minimize side effects.
Administration Tips: Best taken in divided doses with meals. If dry mouth is an issue, take it before meals; if nausea occurs, take it after meals. Avoid abrupt withdrawal.
✔️ Interactions
- Enhanced sedation may occur when used with alcohol, opioids, barbiturates, or cannabis.
- Increased anticholinergic effects when combined with MAOIs or tricyclic antidepressants.
- May increase the risk of tardive dyskinesia when used with neuroleptics.
- Dose adjustments may be necessary with levodopa to avoid dyskinesia.
✔️ Contraindications
- Hypersensitivity to Trihexyphenidyl.
- Patients with narrow-angle glaucoma (risk of blindness)
✔️ Pregnancy & Lactation
Use only if needed. Unknown if excreted in breast milk. May reduce milk production; use with caution in breastfeeding women.
✔️ Precautions
- Monitor for signs of glaucoma before and during treatment.
- Avoid overheating or dehydration, especially in the elderly or those in hot environments.
- Risk of hyperthermia due to anhidrosis exists.
- Monitor closely for signs of NMS when stopping therapy.
✔️ Storage
Keep below 30°C in a dry place away from light.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
