Permethrin 5% is used in the treatment of scabies and head lice.
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Unix 5% Cream, which contains Permethrin, is prescribed for treating scabies in both adults and children aged 2 months and older, as well as crab lice in adults. It functions by effectively eliminating mites, lice, and their eggs, thus curing the infection.
There are some potential side effects associated with Unix 5% Cream, such as itching, redness, and rash at the application site. Typically, these side effects are mild and tend to resolve on their own. If they persist or worsen over an extended period, it's advisable to consult your doctor. It's crucial not to use this medication if you have a known allergy to it.
Unix 5% Cream is intended for external use only. Before applying the cream, ensure that the affected area is clean. Apply a thin layer of the medication gently, following your doctor's instructions. Avoid contact with your eyes, nose, and mouth, as this may cause irritation. Adhere to the prescribed amount; do not exceed it. Thoroughly wash your hands before and after each application. Allow the cream to remain on your skin for 8-12 hours, then wash it off with soap and water. Typically, it is used once a week. If your condition does not improve after the first use, consult your doctor. Be prepared for itching to persist for up to four weeks after treatment.
Please note that Unix 5% Cream is not recommended for children under the age of 2 months due to the absence of safety and efficacy data for this age group. Inform your doctor about any other skin conditions you may have and disclose all your current medications. If you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor before using this medicine.
No interaction was found.
Unix 5% Cream is not recommended for use during pregnancy. Consult your doctor before using.
Unix 5% Cream is not recommended for use in breastfeeding women. Consult your doctor before using.
Unix 5% Cream is not known to affect your ability to drive or use machines.
No interaction was found/established.
No interaction was found/established.
Used to treat:
Unix 5% Cream works by killing microorganisms that cause scabies (an itchy skin condition). It is also effective in paralyzing and killing the lice and their eggs.
Unix 5% Cream has two primary uses:
Scabies: Scabies is a skin condition caused by an infestation of mites that burrow into the skin, lay eggs, and cause itching, redness, and skin irritation. Unix 5% Cream is used in the treatment of scabies to kill the mites and their eggs, thereby relieving the associated symptoms.
Lice Infestation: This cream is also used to treat lice infestations on the scalp and other parts of the skin. It effectively kills lice, making it easier to remove them and prevent their spread.
Permethrin cream is a topical medication used for the treatment of scabies. It contains Permethrin, which is a pyrethroid compound. The mechanism of action involves its effect on nerve cell membranes by disrupting the sodium channel current responsible for membrane polarization. This disruption results in delayed repolarization of the affected cells, ultimately leading to paralysis of the scabies mites.
In terms of pharmacokinetics, Permethrin is intended for topical use only, and there is limited available data on systemic exposure or kinetics following its application to the skin. When applied to the skin, less than 0.5 percent of the Permethrin is absorbed during the initial 48 hours. Any absorbed Permethrin is rapidly metabolized, likely in the liver, through ester hydrolysis. The metabolites are primarily eliminated in the urine. The limited systemic absorption of Permethrin makes it a suitable choice for topical treatment of scabies with minimal risk of systemic side effects.
The recommended duration of treatment for Permethrin cream varies depending on the age group:
Before applying Permethrin cream, ensure that the skin is clean, cool, and dry. Avoid taking a hot shower or bath just before application.
For adults and children over 2 years: Apply the cream to the entire body from the neck down, gently rubbing it into the skin until the cream is absorbed. Ensure that all skin surfaces are covered, including areas between the fingers and toes, under the nails, and on the soles of the feet.
For babies under 2 years: Apply the cream to the face, neck, ears, and scalp, excluding the area immediately around the eyes and mouth.
Leave the cream on for a minimum of 8 hours before washing it off. Reapply to any areas that may have been washed during the 8-hour treatment period, such as after washing hands. If necessary, Permethrin cream should be reapplied after 7 days based on your doctor's advice.
The use of corticosteroids to treat eczema-like symptoms should be avoided before using permethrin because it increases the risk of aggravating the scabies infestation by lowering the immunological response to the mite.
Permethrin is not recommended for people who have a known hypersensitivity to any pyrethroid or permethrin component. Nurses who apply permethrin on a regular basis should wear gloves to protect their hands from discomfort.
In the absence of specific studies on pregnant women, its use in pregnancy should only follow medical advice. It is not known whether permethrin is excreted in human milk so it should not be used in nursing mothers.
Pruritus, edema, and erythema are common symptoms of scabies infestation. Permethrin treatment may temporarily aggravate these symptoms. Patients should be instructed to avoid contact with their eyes while applying the cream and to flush their eyes with water immediately if the cream goes into their eyes.
Store in a cool, dry place, away from light & keep out of the reach of children.
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