Sizonil 1mg Tablet 10pcs

Uses of Sizonil 1mg Tablet

• Anxiety Disorder
• Schizophrenia.

How does Sizonil 1mg Tablet work?

Trifluoperazine, the active component of Sizonil 1, blocks dopamine D2 receptors in the brain, exerting weak anticholinergic and sedative effects alongside strong extrapyramidal and antiemetic effects.

Side Effects of Sizonil 1mg Tablet

Common side effects include restlessness, dystonias, drowsiness, dizziness, and blurred vision. Peripheral edema, blood dyscrasias, and jaundice may rarely occur.

Quick Suggestions:

• Inform your doctor of thyroid or kidney issues, epilepsy, Parkinson's disease, glaucoma, or heart conditions before taking Sizonil 1.
• To maintain consistent medication levels, it's advised to take Sizonil 1 with food at the same time daily, adhering strictly to the prescribed dosage and duration.
• If a dose is missed, it should be taken promptly, and abrupt discontinuation without medical consultation can worsen symptoms.
• Avoid alcohol and sedatives during treatment, and manage weight gain through a balanced diet and regular exercise.
• Uses of Sizonil 1 include treating anxiety disorders and schizophrenia, while side effects may include orthostatic hypotension, drowsiness, dry mouth, abnormal movements, weight gain, increased prolactin levels, urinary retention, constipation, muscle stiffness, and tremors.

Pharmacology:

Trifluoperazine, belonging to the phenothiazine class, primarily acts by blocking dopamine receptors in the central nervous system (CNS), which underlies its antipsychotic and antiemetic effects.

Dosage & Administration of Sizonil 1mg Tablet

For schizophrenia and psychoses, adults typically start with 2-5 mg twice daily, with gradual increases. Children aged 6-12 start with 1 mg twice daily. For severe anxiety, adults may take 1-2 mg twice daily, while children aged 3-12 have adjusted doses based on weight and symptoms. Elderly patients start with reduced doses.

Interaction

Trifluoperazine may interact with drugs like oral anticoagulants, propranolol, and CNS depressants, altering their effects.

Contraindications

Avoid trifluoperazine in comatose patients, those with blood dyscrasias or liver damage, or hypersensitivity to the drug.

Pregnancy & Lactation

Its safety during pregnancy is not established, so use during pregnancy should be carefully considered. Limited data are available regarding its use during lactation.

Precautions & Warnings

Caution is advised when treating elderly patients or those with cardiovascular disease. Careful monitoring for extrapyramidal effects and hypotension is necessary.

Overdose symptoms mainly involve extrapyramidal effects and hypotension. Treatment includes supportive measures and managing symptoms. Anticholinergic drugs can be used for extrapyramidal symptoms, and fluid replacement for hypotension.

Storage Conditions:

Store trifluoperazine at room temperature, away from light and moisture.