Mesalazine 500mg is used in the treatment of ulcerative colitis and Crohn’s disease.
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Mesacol Suppository is an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis. These conditions involve chronic inflammation of the large intestine lining, leading to symptoms such as ulcers, bleeding, and discharge of pus and mucus. The active ingredient, Mesalamine, inhibits the synthesis of inflammatory chemical messengers in the intestines, reducing inflammation, ulceration, bleeding, and stomach pain.
Mesacol Suppository acts locally in the colon and rectum, reducing inflammation and preventing further episodes of ulcerative colitis. Your doctor may recommend lifestyle changes such as avoiding smoking and alcohol, sticking to simple meals, and staying hydrated during treatment. Before starting the treatment, blood and urine tests may be conducted to assess kidney function.
Take Mesacol Suppository after meals, and regular monitoring of liver, kidney, and blood function is essential during treatment. Inform your doctor if you are pregnant or breastfeeding before using Mesacol Suppository. Drink plenty of fluids to prevent dehydration, especially if you experience severe vomiting, diarrhea, fever, or sweating. Common side effects include abdominal pain, nausea, vomiting, bloating, and headache.
Avoid consumption of alcohol while taking Mesacol Suppository
Mesacol Suppository should not be used in pregnant women unless clearly necessary. Consult your doctor before taking it.
Mesacol Suppository should not be used in breastfeeding mothers unless clearly necessary. Consult your doctor before taking it.
Do not drive or operate any machines if your ability is affected by the Mesacol Suppository.
Do not take the Mesacol Suppository if you have a severe kidney impairment. Consult your doctor for advice.
Mesacol Suppository should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Suppository:
Mesacol Suppository contains Mesalamine, an anti-inflammatory agent used to treat and prevent mild-to-moderate Ulcerative colitis. This inflammatory bowel disease causes swelling and inflammation in the bowel, colon, and rectum, leading to symptoms like rectal bleeding, stomach pain, and bloody diarrhea.
Pharmacologically, mesalazine (also known as mesalamine) acts as an anti-inflammatory agent. It belongs to the class of medications called aminosalicylates. The exact mechanism of action of mesalazine in treating inflammatory bowel diseases like ulcerative colitis is not fully understood, but it is believed to involve several processes.
Inhibiting Prostaglandin Production: Prostaglandins are chemical messengers in the body that contribute to inflammation. Mesalazine is believed to inhibit the production of prostaglandins in the intestines, reducing inflammation and swelling.
Modulating Immune Response: Mesalazine may also modulate the immune response in the intestinal mucosa. It helps to regulate the activity of immune cells involved in the inflammatory process, thereby reducing the overall inflammatory response.
Scavenging Free Radicals: Mesalazine has antioxidant properties, which means it can neutralize harmful molecules called free radicals. Free radicals can contribute to tissue damage and inflammation, and mesalazine's antioxidant effects may help mitigate these effects.
Maintaining Mucosal Barrier: Mesalazine may contribute to the maintenance of the mucosal barrier in the intestines. This barrier is important for protecting the intestinal lining and preventing the penetration of harmful substances.
May interact with non-steroidal anti-inflammatory drugs, immunosuppressants, anticoagulants, and laxatives.
Inform the doctor of any allergies, conditions, or medications.
Consult your doctor before use during pregnancy or breastfeeding.
Store Mesacol Suppository 5's in a cool, dry place away from sunlight.
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