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Amenamevir acts by inhibiting the viral helicase–primase complex, an enzyme crucial for viral DNA unwinding and primer synthesis during replication. This mechanism differs from standard antivirals such as acyclovir and valaciclovir, which inhibit viral DNA polymerase.
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ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
- ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Amenavir tablet is used for the treatment of herpes simplex infection, recurrent herpes simplex, and herpes zoster (shingles). Due to its novel mechanism of action, it is a useful alternative for patients who have developed resistance to conventional antiviral agents.
✔️ Dosage & Administration
Herpes simplex: 200 mg orally once daily after meals.
Recurrent herpes simplex: A single 1200 mg dose after meals, taken within 6 hours of symptom onset.
Herpes zoster: 400 mg orally once daily after meals.
Pediatric use: Safety and efficacy in children have not been established.
✔️ Side Effects
Common: Headache, nausea, diarrhea, abdominal pain, skin reactions, increased urinary biomarkers
Serious: Thrombocytopenia, gingival bleeding, palpitations
✔️ Interaction
Amenavir is metabolized mainly via CYP3A4:
Ketoconazole (CYP3A4 inhibitor): Increases Amenavir plasma levels.
Rifampicin (CYP3A4 inducer): Reduces Amenavir concentration and efficacy.
Midazolam: Plasma levels may be reduced when co-administered.
Warfarin: No clinically significant interaction observed.
✔️ Contraindications
Severe renal impairment
Known hypersensitivity to amenamevir or any formulation component
✔️ Pregnancy & Lactation
Pregnancy: Animal studies showed no significant fetal harm, but adequate human data are lacking.
Lactation: Safety during breastfeeding has not been established.
✔️ Careful monitoring is advised in:
Patients with severe renal impairment
Patients with thrombocytopenia
Elderly individuals
✔️ Storage Conditions
Store below 30°C in a dry place. Protect from light and moisture. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
