Onaseron ODT | Ondansetron 4mg | 10pcs | ePharma
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Onaseron ODT Tablet 10pcs

Generic: Ondansetron

Type: Tablet

Pack Size: 10 Pcs

Onaseron, a serotonin subtype 3 (5-HT3) receptor antagonist, is indicated for:

  • Preventing nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.
  • Preventing and treating post-operative nausea and vomiting.
  • Preventing radiotherapy-induced nausea and vomiting.

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Discount Price: ৳ 47
MRP: ৳ 50 6% Off

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✅ Description:

Onaseron ODT Tablet contains Ondansetron, which belongs to a group of medicines called Anti-Nausea. It is used to manage nausea and vomiting induced by chemotherapy or radiotherapy. Onaseron ODT Tablet is also used after surgeries (operations) to manage nausea and vomiting.

Before taking the Onaseron ODT Tablet, inform your doctor if you have severe constipation, heart or liver problems, imbalance with the levels of salts in the blood, such as potassium, sodium, and magnesium, or have been scheduled for any surgery.

Onaseron ODT Tablet is not recommended for use during pregnancy. This medicine may pass through the breast milk hence it is not recommended during breastfeeding. Consult your doctor before taking this medicine.

The dose of Onaseron ODT Tablet will depend on your child's age, body weight, and disease condition. Dosage adjustment is not required in elderly patients, hence consult your doctor before taking Onaseron ODT Tablet.

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✔️ Side Effects

Common side effects include headache, constipation, and diarrhea, usually mild to moderate. Rash, sensation of warmth, hiccups, and liver enzyme abnormalities have been reported. Rarely, anaphylaxis, bronchospasm, tachycardia, angina, hypokalemia, and shortness of breath may occur. Extrapyramidal reactions are very rare.

✔️ Pharmacology

Ondansetron is a potent and highly selective 5-HT3 receptor antagonist. Its precise mode of action in controlling nausea and vomiting is not fully known. Chemotherapeutic agents and radiotherapy can release 5-HT in the small intestine, initiating a vomiting reflex via 5-HT3 receptors on vagal afferents. Ondansetron blocks this reflex. The release of 5-HT in the area postrema (brainstem) may also contribute to emesis through a central mechanism. Thus, ondansetron likely manages nausea and vomiting by antagonizing 5-HT3 receptors in both the peripheral and central nervous systems. The mechanism for post-operative nausea and vomiting may involve similar pathways.

✔️ Radiotherapy-Induced Nausea and Vomiting:
  • Adults:
    • Tablets/Oral Solution: 8 mg 1-2 hours before radiotherapy, then 8 mg every 8 hours for up to 5 days.
✔️ Postoperative Nausea and Vomiting:
  • Adults:
    • Tablets: 16 mg given as two 8 mg tablets.
    • Injection: 4 mg.
  • Pediatrics (>40 kg): Injection: 4 mg.
  • Pediatrics (<40 kg): Injection: 0.1 mg/kg.
✔️ Chemotherapy-Induced Nausea and Vomiting:
  • Adults and Pediatric (6 months to 18 years):
    • Tablets/Oral Solution: Three 0.15 mg/kg doses, up to 16 mg per dose.
    • Injection: Three 0.15 mg/kg doses, up to 16 mg per dose, infused intravenously over 15 minutes.
✔️ Directions for Use:

It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush, or chew it. 

✔️ Before taking Onaseron ODT Tablet, inform your doctor, if you are taking any of the following medicine:
  • Apomorphine (used to manage Parkinson’s disease)
  • Medicines used to manage epilepsy (Ex. phenytoin, carbamazepine)
  • Medicines used to manage lung infections like Tuberculosis (Ex. rifampicin)
  • Tramadol, methadone (medicine used to provide relief from pain)
  • Medicines used for psychotic disorders (Ex. haloperidol)
  • Medicines used to manage heart problems such as abnormal heartbeats (Ex. amiodarone) and/or high blood pressure (Ex. atenolol, timolol)
  • Cancer medicines (Ex. doxorubicin, daunorubicin, monoclonal, trastuzumab)
  • Erythromycin, ketoconazole (used to manage infections)
  • Medicines used to manage depression and anxiety (ex. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine escitalopram)
✔️ Contraindications

Onaseron is contraindicated in patients with hypersensitivity to the drug or its components and in those taking apomorphine

✔️ Pregnancy & Lactation

Animal studies have not shown evidence of harm to the fetus, but there are no adequate studies in pregnant women. Ondansetron is excreted in rat milk, so caution is advised when administering it to breastfeeding women

✔️ Use in Special Populations
  • Renal impairment: No dosage adjustment is necessary.
  • Hepatic impairment: Maximum daily dose is 8 mg for severe impairment.
  • Children (≤4 years): Limited data available.
  • Elderly (>65 years): No dosage adjustment is needed.
✔️ Precautions & Warnings

Hypersensitivity reactions have been reported in patients sensitive to other 5-HT3 antagonists. Onaseron should not replace nasogastric suction in cases of gastric or intestinal peristalsis issues. It may mask progressive ileus or gastric distension post-abdominal surgery or chemotherapy-induced nausea and vomiting. 

✔️ Storage Conditions

Store below 30ºC in a dry place, protected from light and moisture.

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Check our pricing section for Onaseron ODT Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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