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Paloxi-IV 0.25 Injection contains Palonosetron which belongs to a group of medicines called Serotonin antagonists. It is used to control nausea and vomiting that occurs as a result of chemotherapy (treatment of cancer). Paloxi-IV 0.25 Injection is also used for Postoperative nausea and vomiting following surgery.
The interaction of alcohol with Paloxi-IV 0.25 Injection is unknown. Please consult a doctor before consuming alcohol with Paloxi-IV 0.25 Injection.
Paloxi-IV 0.25 Injection is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please inform your doctor if you are pregnant.
It is not known whether Paloxi-IV 0.25 Injection passes through breast milk, hence consult your doctor before receiving this medicine.
Paloxi-IV 0.25 Injection may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking Paloxi-IV 0.25 Injection.
Paloxi-IV 0.25 Injection may be safe to use in patients with kidney problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.
Paloxi-IV 0.25 Injection may be safe to use in patients with liver problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.
Paloxi-IV 0.25 Injection blocks the action of serotonin, which induces nausea and vomiting (serotonin is a chemical that carries messages between nerve cells in the brain and throughout the body).
Palonosetron is used to treat-
Palonosetron is a medication that blocks the 5-HT3 receptor, which is responsible for causing nausea and vomiting when stimulated by serotonin released from cells in the small intestine due to chemotherapy. This drug has a strong affinity for the 5-HT3 receptor and does not affect other receptors.
Typical dosage:
Nausea and vomiting caused by chemotherapy:
Paloxi-IV 0.25 Injection will be injected intravenously into your body only by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending on your age, body weight, and disease condition.
In controlled clinical trials, palonosetron injection was administered safely with corticosteroids, analgesics, antiemetics/antinauseants, antispasmodics, and anticholinergic agents. Palonosetron had no effect on the antitumor activity of cisplatin, cyclophosphamide, cytarabine, doxorubicin, or mitomycin C in murine tumor models.
Palonosetron is not recommended for patients who have a history of hypersensitivity to the drug or any of its ingredients.
Store at or below 30°C, away from light and moisture. Keep out of reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.