Progest 10mg Tablet

✔️ Uses of Progest 10mg Tablet

• Relieves menstrual pain
• Treats symptoms of endometriosis and premenstrual syndrome
• Treats infertility and irregular menstrual periods
• Treats signs of menopause in postmenopausal women
• Prevents unusually heavy or long periods during menopause

✔️ How does Progest 10mg Tablet work?

Progest 10mg Tablet works by imitating the activities of the natural hormone progesterone, which in turn helps to treat conditions caused due to hormonal imbalance in the body.

✔️ Side Effects of Progest 10mg Tablet

• Vaginal bleeding
• Migraine
• Headache
• Nausea
• Vomiting
• Stomach pain
• Menstrual disorders
• Breast pain
• Breast tenderness

✔️ Quick Suggestions:

• Progest helps treat disorders related to the female reproductive cycle, infertility, irregular menses, and uterine bleeding.
• Determine the cause of abnormal uterine bleeding before you begin Progest 10mg Tablet treatment. In the early stages of treatment, the medicine may result in breakthrough bleeding and spotting.
• Progest 10mg Tablets can be used by pregnant women only when prescribed by a doctor.
• The tablet should be taken at the same time each day. This will ensure that there is a constant amount of this medicine in the body.
• You should not take Progest 10mg Tablet and epilepsy medicines like phenobarbital, phenytoin, and carbamazepine.

✔️ Indication of Progest 10mg Tablet

Progest 10mg Tablet is prescribed for various gynecological conditions and hormonal imbalances in women. Here's a summary of its uses:

• Dysmenorrhoea (Menstrual Pain): Progest 10mg Tablet is used to treat severe pain and cramps in the lower abdomen during menstruation.
• Endometriosis: It's prescribed for endometriosis, a condition where endometrial tissue grows outside the uterus, causing symptoms like painful urination, stomach cramps, and menstrual pain.
• Secondary Amenorrhoea: In cases of secondary amenorrhoea (absence of menstrual cycles for 3 or 6 months due to conditions like polycystic ovary syndrome), Progest 10mg Tablet helps by addressing hormonal imbalances.
• Menstrual Abnormalities: Progest 10mg Tablet is used to treat menstrual irregularities such as premenstrual syndrome (PMS), irregular periods, and abnormal blood loss.
• Dysfunctional Uterine Bleeding: It's prescribed for abnormal uterine bleeding, characterized by heavy or irregular bleeding due to hormonal changes, fibroids, or other factors.
• Threatened Abortion: In cases of vaginal bleeding during early pregnancy (threatened abortion), Progest 10mg Tablet may be used to prevent the risk of miscarriage.
• Habitual Abortion: Progest 10mg Tablet can be used in the treatment of habitual or recurrent abortion, which involves three or more consecutive pregnancy losses.
• Infertility Due to Luteal Insufficiency: Progest 10mg Tablet is employed in treating infertility caused by luteal insufficiency, where there is insufficient progesterone hormone secretion.
• Hormone Replacement Therapy: It's used in combination with estrogen as hormone replacement therapy for women experiencing low levels of estrogen and progesterone, often due to menopause (natural or surgical).

Remember, Progest 10mg Tablet should always be taken under a doctor's guidance, and the dosage and duration of treatment will be determined based on your specific condition. It is important to follow your doctor's instructions for the best results and to monitor any potential side effects or changes in your health.

✔️ Pharmacology

Dydrogesterone is an orally active progestogen that creates a full secretory endometrium in an estrogen-primed uterus, hence protecting against estrogen-induced endometrial hypertrophy and carcinogenesis. It's used to treat endogenous progesterone insufficiency in all situations. Dydrogesterone doesn't have any oestrogenic, androgenic, thermogenic, anabolic, or corticoid properties.

✔️ Dosage & Administration of Progest 10mg Tablet

Progest 10mg Tablet should always be taken according to your doctor's prescription. Here are the recommended dosages for various conditions:

• Threatened miscarriage: Start with 40 mg (four tablets) at once, followed by 10 mg (one tablet) every eight hours until symptoms improve.
• Habitual miscarriage: Take 10 mg (one tablet) twice daily until the twentieth week of pregnancy.
• Dysmenorrhoea (Menstrual pain): Use 10 mg (one tablet) twice daily from day 5 to day 25 of the menstrual cycle.
• Endometriosis: Take 10 mg (one tablet) two or three times daily from day 5 to day 25 of the cycle or continuously.
• Dysfunctional bleeding (to arrest bleeding): Use 10 mg (one tablet) twice daily for five to seven days. The presentation should be given with estrogen.
• Dysfunctional bleeding (to prevent bleeding): Take 10 mg (one tablet) twice daily from day 11 to day 25 of the cycle. The presentation should be given with estrogen.
• Amenorrhoea: Combine with estrogen once daily from day 1 to day 25 of the cycle, along with 10 mg Presentation twice daily from day 11 to day 25 of the cycle.
• Irregular cycles: Use 10 mg (one tablet) twice daily from day 11 to day 25 of the cycle.
• Infertility due to luteal insufficiency: Take 10 mg (one tablet) daily from day 14 to day 25 of the cycle. Continue this treatment for at least 6 consecutive cycles. If you become pregnant, continue the treatment during the first month of pregnancy using the specified doses for habitual miscarriage.
• Luteal support as part of Assisted Reproductive Technology (ART) treatment: Take 10 mg three times daily (three tablets daily) starting on the day of oocyte retrieval. Continue for 10 weeks if pregnancy is confirmed.
• Hormone Replacement Therapy: The dosing varies depending on the type of estrogen therapy you are on. Consult your doctor for guidance.

Important Notes:

• If endometrial biopsies or ultrasound reveal inadequate Presentational response, your doctor may prescribe 20 mg of Dydrogesterone.
• Dydrogesterone is not recommended before menarche (the first occurrence of menstruation).
• The safety and efficacy of Dydrogesterone in adolescents aged 12 to 18 years have not been established.

Always adhere to your doctor's instructions and consult them if you have any doubts about your treatment with Presentation 10 mg Tablet.

✔️ Interaction

Before taking Progest 10mg Tablet, it's crucial to inform your doctor about any other medications or herbal supplements you may be taking. This is important to ensure that there are no potential interactions or adverse effects when combining these treatments. Specifically, you should let your doctor know if you are taking:

• Medicines Used to Treat Epilepsy: This includes medications like phenobarbital, phenytoin, and carbamazepine, which are used to manage seizures and epilepsy.
• Medicines Used to Treat Tuberculosis: Rifampicin and rifabutin are commonly used drugs for tuberculosis treatment, and your doctor should be aware if you're taking any of these.
• Medicine Used to Treat HIV Infection: Antiretroviral drugs used to manage HIV infection, such as nevirapine, efavirenz, ritonavir, and nelfinavir, can interact with other medications, so your doctor needs this information to ensure your safety.
• St. John’s Wort: St. John's Wort is an herbal remedy used to treat depression. It can interact with various medications, so your doctor should be aware if you're taking it.
• Other Herbal Medicines: Mention any other herbal supplements you're using, such as sage or ginkgo biloba, as these can also potentially interact with Progest 10mg Tablet or other medications.

✔️ Contraindications

• If you are allergic to dydrogesterone or other ingredients of Progest 10mg Tablet
• If you have a known or suspected history of tumors like meningioma.
• If you have vaginal bleeding whose cause is not determined.

✔️ Pregnancy & Lactation

The safety of Dydrogesterone during pregnancy is generally considered to be good based on available data. Exposure to Dydrogesterone during pregnancy in over 10 million cases has not been associated with reported harm to the fetus. This suggests that Dydrogesterone is relatively safe to use during pregnancy when prescribed by a healthcare professional.

However, the excretion of Dydrogesterone in breast milk is not well-documented, and it is known that progestogens, including Dydrogesterone, can transfer to breast milk in small amounts. While the risk to a nursing infant from exposure to these small amounts is generally considered low, there is limited information available on the safety of Dydrogesterone during lactation. As a result, it is advisable to avoid the use of Dydrogesterone during breastfeeding unless recommended by a healthcare provider.

Pregnant or breastfeeding individuals should always consult their healthcare provider before starting or discontinuing any medication to ensure the best course of action for their specific situation and the safety of both the mother and the baby.

✔️ Precautions & Warnings

The use of Dydrogesterone may require close monitoring in individuals with certain medical conditions or who are at risk of specific adverse effects. Here are some key points to consider:

• Loss of Vision: Dydrogesterone use should be closely monitored for any signs of visual disturbances or loss of vision. If such symptoms occur, immediate medical attention is advised.
• Proptosis: Proptosis refers to the bulging of the eyeballs, often associated with conditions like thyroid eye disease. Individuals with proptosis should be monitored while taking Dydrogesterone.
• Diplopia: Diplopia is double vision, where a person sees two images of a single object. If diplopia occurs during Dydrogesterone treatment, it should be evaluated by a healthcare provider.
• Migraine: Migraine headaches should be monitored in individuals taking Dydrogesterone. If migraines worsen or become more frequent, medical attention is needed.
• Signs and Symptoms of Embolic Disorders: Individuals should be monitored for any signs or symptoms of embolic disorders (conditions where blood clots or particles block blood vessels). Such symptoms may include chest pain, shortness of breath, leg swelling, or other signs of vascular problems.
• Cardiovascular Disease (CVD) or Renal Impairment: Patients with a history of cardiovascular disease or renal (kidney) impairment may need closer monitoring while using Dydrogesterone, as it can impact fluid retention.
• Epilepsy: Individuals with epilepsy should be monitored carefully during Dydrogesterone treatment, as the medication may affect their condition.
• Asthma: Asthma patients should be monitored, as Dydrogesterone may potentially exacerbate their condition due to its effects on fluid retention.
• Lactation: Dydrogesterone use during lactation is generally not recommended, as progestogens like Dydrogesterone can transfer to breast milk. It's important to discuss this with a healthcare provider to assess the potential risks and benefits.
• Progest 10mg Tablet should be used in post-pubertal female children, typically aged between 12-18 years, only if prescribed by a physician. It is not intended for use in male children or in female children who have not yet reached puberty. Therefore, it's essential to consult your doctor before considering the use of this medication in adolescent girls, and only use it under their guidance and prescription.

✔️ Storage Conditions

Store below 30°C in a dry, light-protected location. Keep out of children's reach.