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Dexamox Ophthalmic Solution 5ml
Dexamox Ophthalmic Solution (Moxifloxacin Hydrochloride + Dexamethasone)
Each 1 mL contains:
- Moxifloxacin Hydrochloride BP (equivalent to Moxifloxacin 5 mg)
- Dexamethasone Sodium Phosphate USP (equivalent to Dexamethasone Phosphate 1 mg)
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✅ Description:
Moxifloxacin is a fourth-generation fluoroquinolone with broad-spectrum antibacterial activity. It works by inhibiting DNA gyrase (topoisomerase II) and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, and repair.
Dexamethasone is a corticosteroid that reduces inflammation. It contains a methyl group at the 16-alpha position and a fluorine atom at the 9-alpha position, enhancing its potency. It has anti-allergic, anti-exudative, and anti-proliferative effects. It works by inhibiting phospholipase A2, which prevents the production of inflammatory prostaglandins. Additionally, it reduces neutrophil infiltration at inflammation sites.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Moxifloxacin & Dexamethasone eye drops are prescribed for:
- Treatment of eye infections caused by susceptible microorganisms.
- Prevention of bacterial infections and inflammation following eye surgery.
✔️ Side Effects of Dexamox Ophthalmic Solution
Moxifloxacin-related:
- Conjunctivitis
- Decreased visual clarity
- Dry eyes
- Keratitis
- Eye discomfort
- Redness (hyperemia)
- Eye pain
- Subconjunctival hemorrhage
- Excessive tearing
Dexamethasone-related:
- Blurred vision or defects in the visual field
- Cataract formation
- Secondary eye infections due to immune suppression
- Perforation of the eyeball in some cases
✔️ Dosage & Administration of Dexamox Ophthalmic Solution
For post-surgical infection prevention & inflammation control:
- Before eye surgery: Instill 1 drop, 4 times daily, starting 1 day before surgery and continue for 15 days after surgery.
For cataract surgery patients:
- On the day of surgery: Administer immediately after the procedure.
For LASIK refractive surgery patients:
- On the day of surgery: Administer at least 15 minutes after the procedure.
For bacterial eye infections:
Instill 1 drop, 4 times daily for up to 7 days.
Note: Always follow the dosage prescribed by a registered physician.
Elderly Patients: No dosage adjustment is required.
Children: Safety and effectiveness in pediatric patients have not been established.
✔️ Dexamox Ophthalmic Solution should not be used in patients with:
- Allergies to quinolones or any components of the formulation.
- Glaucoma or conditions that cause thinning of the cornea or sclera.
- Viral eye infections, including:
- Epithelial herpes simplex keratitis (dendritic keratitis)
- Vaccinia and varicella infections
- Other viral diseases of the cornea and conjunctiva
- Mycobacterial or fungal eye infections.
✔️ Use in Pregnancy & Lactation
- There are no well-controlled studies on the use of Moxifloxacin & Dexamethasone eye drops in pregnant women.
- Use only if the potential benefits outweigh the risks to the fetus.
- Caution is advised for nursing mothers.
✔️ Precautions & Warnings
Discontinue use if an allergic reaction occurs and consult a doctor.
Prolonged steroid use may lead to:
- Increased intraocular pressure (IOP), leads to glaucoma and optic nerve damage.
- Visual defects and cataract formation.
- Increased risk of secondary infections.
- Regular eye pressure monitoring is necessary for long-term users.
- Patients with corneal or scleral thinning should be used with caution, as perforations may occur.
- In acute purulent eye conditions, steroids may mask infections or worsen existing ones.
✔️ Storage Instructions
- Store below 30°C, away from direct light.
- Once opened, use within 28 days.
- Can be stored at room temperature (below 30°C) after opening.
- Discard after 28 days.
- Keep out of reach of children.
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