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Nepanil 0.1% Ophthalmic Suspension 5ml
Nepanil is a non-steroidal anti-inflammatory prodrug, which is converted into amfenac, an agent that inhibits prostaglandin production, reducing pain and inflammation.
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✅ Description:
Safety Advices
Alcohol
UNSAFE
Avoid consuming alcohol as it is unknown whether Nepanil 0.1% Ophthalmic Suspension interacts with alcohol or not.
Pregnancy
CONSULT YOUR DOCTOR
During pregnancy, Nepanil 0.1% Ophthalmic Suspension can only be used when prescribed during the first 6 months by the doctor. Nepanil can not be used during the last 3 months of pregnancy as it may harm a fetus.
Breastfeeding
CONSULT YOUR DOCTOR
Nepanil 0.1% Ophthalmic Suspension can only be used in breastfeeding women if suggested by the doctor as it is unknown whether this drug passes into breast milk.
Driving
SAFE
Nepanil 0.1% Ophthalmic Suspension may cause blurred vision, so one should avoid driving after using this medicine.
Kidney
SAFE
NEPAFENAC is safe to use if prescribed by the doctor.
Liver
SAFE
Nepanil 0.1% Ophthalmic Suspension is safe to use if prescribed by the doctor.
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✔️ Uses of Nepanil 0.1% Ophthalmic Suspension
Relief of post-operative eye pain and inflammation.
✔️ How does Nepanil 0.1% Ophthalmic Suspension work?
Nepanil is a non-steroidal anti-inflammatory drug (NSAID). It blocks the release of chemical messengers responsible for pain and inflammation (redness and swelling) in the eye.
✔️ Side Effects of Nepanil 0.1% Ophthalmic Suspension
Reported side effects include foreign body sensation, eyelid margin crusting, ocular discomfort, and ocular redness (hyperemia).
✔️ Word of Advice
- Nepanil is prescribed for post-operative eye pain and inflammation relief.
- After applying the drops, apply pressure to the corner of the eye (near the nose) for 1 minute.
- A course of treatment typically lasts 4 to 6 weeks.
- Wait 5 to 10 minutes between using different eye medications to avoid dilution.
- Stinging may occur for 1-2 minutes; inform your doctor if it persists.
- Let your doctor know if you are on blood thinners or have bleeding problems.
- Use the drops within 4 weeks of opening the bottle.
✔️ Indication of Nepanil 0.1% Ophthalmic Suspension
Nepanil 0.1% Sterile Ophthalmic Suspension: Used for treating postoperative ocular pain and inflammation, including after cataract surgery. It also helps in the prevention of surgery-induced miosis and postoperative cystoid macular edema (CME).
✔️ Pharmacology
Nepafenac is a nonsteroidal anti-inflammatory drug (NSAID) in prodrug form. After being applied to the eye, it penetrates and converts into its active form, inhibiting the enzyme necessary for prostaglandin synthesis, which reduces pain and inflammation.
✔️ Dosage & Administration of Nepanil 0.1% Ophthalmic Suspension
Nepafenac 0.1% Suspension:
- For post-operative pain & inflammation: Instill 1 drop 3 times daily, starting 1 day before surgery and continuing through the first 2 weeks post-operation.
- For surgery-induced miosis: Instill 1 drop 3 times daily, beginning 1 day before surgery and continuing on the day of surgery.
- For post-operative CME prevention: Instill 1 drop 3 times daily, starting 1 day before surgery and continuing for 6 weeks after surgery.
- Children: The safety and effectiveness of Nepafenac in patients under 18 years have not been established.
- Elderly: No significant difference in safety or efficacy has been observed between elderly and younger patients.
✔️ Interaction of Nepanil 0.1% Ophthalmic Suspension
Inform the doctor if you are taking blood thinners (warfarin), antiplatelet medications (clopidogrel), corticosteroid drugs (prednisone), and other eye medications (corticosteroid eye drops).
Inform the doctor if you have diabetes, dry eye syndrome, an allergy to any other eye drops, arthritis, or a bleeding or blood-clotting disorder, such as hemophilia.
✔️ Contraindications
Not to be used in patients with hypersensitivity to any component of the formulation or other NSAIDs.
✔️ Pregnancy & Lactation
- Pregnancy: There are no adequate studies in pregnant women. Nepafenac should only be used if the potential benefits justify the risks to the fetus.
- Lactation: It is unclear if this drug is excreted in human milk, so caution should be used when administered to nursing mothers.
✔️ Precautions & Warnings
Nepanil should be used cautiously in patients with bleeding tendencies or those on medications that may prolong bleeding time.
✔️ Storage:
Store in a cool and dry place away from sunlight
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