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✅ Description:
Indications
Ketotifen eye drop is used to treat the signs and symptoms of allergic conjunctivitis, such as vernal keratoconjunctivitis, vernal keratitis, blepharitis, blepharon conjunctivitis, and giant papillary conjunctivitis (itchy, watery, red, swollen eyes and eyelids).
Pharmacology
Ketotifen is a powerful anti-allergic drug that blocks histamine (H1) receptors in a non-competitive and long-lasting manner. Ketotifen works by preventing the release of mediators (such as histamine, leukotrienes, and prostaglandins) from cells that cause type I allergic reactions. Ketotifen also stabilizes mast cells, reduces chemotaxis, and activates eosinophil degranulation.
Dosage & Administration
Adults and children 3 years and older: 1 drop in the affected eye(s) twice daily, every 8-12 hours, not more than twice per day.
Children under 3 years of age: Consult with a doctor.
Interaction
If Ketotifen eye drops are taken in conjunction with other eye treatments, at least 5 minutes must pass between the two medications.
Contraindications
Ketotifen hypersensitivity or hypersensitivity to any of the components
Side Effects
Burning, stinging, punctate corneal epithelial erosion, blurred vision after drug instillation, dry eyes, eyelid dysfunction, conjunctivitis, eye pain, photophobia, and subconjunctival hemorrhage are all common adverse effects.
Pregnancy & Lactation
There is insufficient information about the usage of ketotifen eye drops in pregnant women. Systemic levels are significantly lower after ocular administration than after oral treatment. Prescriptions for pregnant women should be handled with caution. Although animal research shows excretion into breast milk after oral administration, topical application to humans is unlikely to yield detectable amounts in breast milk. During lactation, ketotifen 0.25 percent eye drops can be utilized.
Precautions & Warnings
This eye drop should not be used while the patient is wearing lenses because benzalkonium chloride, a preservative in the formulation of Ketotifen 0.025 percent eye drops, may deposit in soft contact lenses. Before using the drops, take out the lenses, and wait at least 15 minutes before putting them back in.
Storage Conditions
Protect from light and moisture by storing in a cool, dry location. Keep out of children's reach. Because touching the dropper tip to any surface can contaminate the solution, avoid doing so. After 30 days from the date of initial opening, do not use.
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