Ketoconazole treats fungal infections of the scalp and body such as dandruff, dry or greasy scaling of the scalp and other parts of the body called seborrhoeic dermatitis
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Nizoder 2% Shampoo is specifically designed to treat dandruff and alleviate associated symptoms like flaking, scaling, and itching. Its active ingredient is ketoconazole, an antifungal medication that has been clinically proven to effectively control dandruff. By targeting the growth of fungus, which is the underlying cause of dandruff, Nizoder 2% Shampoo not only addresses the symptoms but also tackles the root problem.
Similar shampoos containing ketoconazole as their active ingredient include Nizoral shampoo, Ketocip shampoo, Nizol shampoo, and Exizol shampoo. It's important to note that Nizoder 2% Shampoo should only be used under medical supervision and not as a regular shampoo. To use it correctly, thoroughly wet your hair and scalp before applying the shampoo. Massage it into the scalp and hair for at least three minutes before rinsing it off with water.
Possible side effects of using Nizoder 2% Shampoo may include dryness, irritation, or redness of the scalp. If these symptoms worsen or persist, seeking medical assistance is recommended. Pregnant or nursing individuals should useNizoder 2% Shampoo only if prescribed by a doctor.
It is crucial to avoid applying Nizoder 2% Shampoo to broken or irritated skin, and always follow the instructions provided by your doctor or pharmacist. If you experience any unusual symptoms or side effects, discontinue the use of the shampoo immediately and consult your doctor.
No interaction found/established
Nizoder 2% Shampoo should not be used during pregnancy unless considered necessary by your doctor. Do not use it without consulting your doctor.
Use of Nizoder 2% Shampoo while breastfeeding poses little or no risk to the breastfed infant.
Nizoder 2% Shampoo is a topical preparation and may not affect the driving ability or ability to handle machinery.
No interaction found/established
No interaction found/established
Nizoder 2% Shampoo exerts its antifungal effects by binding to fungal p450 enzymes, thereby inhibiting their activity. These enzymes are involved in the synthesis of ergosterol, a vital component of the fungal cell wall. By inhibiting the production of ergosterol, Nizoder 2% Shampoo prevents the growth and replication of fungal cells. As a result, the fungi responsible for causing dandruff are unable to thrive and sustain their growth. This mechanism of action helps control fungal overgrowth, reducing dandruff and its associated symptoms.
Ketoconazole 2% Shampoo is primarily used to treat and prevent infections caused by the yeast Malassezia (previously known as Pityrosporum). It is specifically indicated for the following conditions:
Tinea Versicolor (Focal): Ketoconazole shampoo is effective in treating tinea versicolor, a fungal infection that causes discolored patches on the skin. The shampoo helps control the growth of Malassezia yeast, thereby reducing the symptoms of tinea versicolor.
Seborrheic Dermatitis: This shampoo is also used for the treatment of seborrheic dermatitis, a common skin condition characterized by redness, itching, and flaking of the scalp, face, and other areas. Ketoconazole shampoo helps to alleviate the symptoms associated with seborrheic dermatitis by targeting the underlying fungal infection caused by Malassezia.
Dandruff (Hair Disease): Ketoconazole shampoo is an effective option for treating dandruff, a common scalp condition characterized by flaking and itching. It helps to control the overgrowth of Malassezia yeast on the scalp, reducing flaking and relieving itching associated with dandruff.
Ketoconazole 2% shampoo is a synthetic antifungal agent belonging to the imidazole dioxolan class. It exhibits broad-spectrum activity against various dermatophytes (filamentous fungi) and yeasts commonly found on the skin. Ketoconazole works by altering the permeability of the cell membrane in these fungi, leading to their suppression and inhibition of growth.
The dermatophytes targeted by ketoconazole 2% shampoo include Trichophyton rubrum, T. mentagrophytes, T. tonsurans, Microsporum canis, M. audouini, M. gypseum, and Epidermophyton floccosum. It is also effective against yeast species such as Candida albicans, Pityrosporum ovale (also known as Malassezia ovale), and C. tropics. Additionally, ketoconazole is effective against Malassezia furfur (formerly known as Pityrosporum orbiculare), the organism responsible for causing conditions like ringworm.
By targeting a wide range of fungi and yeasts, ketoconazole 2% shampoo helps combat various fungal skin infections, including dandruff (associated with Pityrosporum ovale), dermatophytosis (ringworm), and candidiasis. Its ability to modify the cell membrane permeability of these organisms contributes to its antifungal activity and effectiveness in treating these conditions.
For the treatment of seborrheic dermatitis, the cream should be applied twice daily (every 12 hours) for a duration of 4 weeks or until the condition clears. The shampoo should be applied twice weekly, with at least 3 days between each application, for a total of 4 weeks.
To treat tinea versicolor using the shampoo, wet your hair and massage the shampoo into the scalp for 1 minute. Rinse it off and repeat the process, leaving the shampoo on the scalp for an additional 3 minutes. This should be done twice weekly for 4 weeks, with at least 3 days between each shampoo application.
For tinea corporis, tinea cruris, and tinea pedis, the cream should be applied once daily to the affected area for a duration of 2 weeks (6 weeks for tinea pedis). Ensure that the affected area is adequately covered with the cream.
When using the Ketoconazole shampoo, follow these steps:
Please note that the dosing and administration instructions for children with seborrheic dermatitis are not established, while for those above 12 years, the shampoo should be applied twice weekly with at least 3 days between each shampoo, and the cream should be applied to the affected area every 12 hours for 4 weeks.
If you are allergic to ketoconazole or any other contents of Nizoder 2% Shampoo
Since ketoconazole is not absorbed through the skin after application, pregnancy and lactation are not contraindications to the use of ketoconazole 2% shampoo.
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