Micosina 2% Oral Gel is indicated for:
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
Micosina 2% Oral Gel, containing miconazole, is an antifungal agent used to treat fungal and associated bacterial infections of the skin and nails. These infections can occur on the trunk, hands, feet, scalp, outer ear, and groin, including conditions such as athlete’s foot, dhobie itch, intertrigo, and infected nappy rash. The gel also has moisturizing properties that help soothe cracked, red skin.
Skin infections typically improve within 2 to 6 weeks. If there is no improvement after this period, consult a doctor for further advice.
Candidiasis is a fungal infection caused by Candida species, particularly Candida albicans. This gel is effective in treating candidiasis affecting the mouth (oral candidiasis) and the gastrointestinal tract.
A-Migel oral gel helps eliminate fungal colonization in both the mouth and the gastrointestinal tract. Fungal colonization refers to the presence and growth of fungi without causing infection. This gel helps in clearing such colonization and preventing potential infections.
Superinfections occur when a new infection develops on top of an existing one. A-Migel oral gel is effective in treating superinfections caused by gram-positive bacteria. Gram-positive bacteria include species like Staphylococcus aureus and Streptococcus pyogenes, which can cause various infections, including those of the mouth and gastrointestinal tract.
Pharmacodynamics: Miconazole has antifungal properties effective against common dermatophytes and yeasts, and antibacterial properties against certain gram-positive bacilli and cocci. It functions by inhibiting a demethylation step in the biosynthesis of ergosterol, a key component of fungal cell membranes. This disruption creates holes in the membrane, causing essential components to leak out and ultimately resulting in the death of the fungal cells.
Pharmacokinetics: Miconazole has low oral bioavailability (25-30%) due to limited absorption from the intestinal tract. Once administered as an oral gel, it is systemically absorbed and primarily binds to plasma proteins (88.2%), especially serum albumin and red blood cells (10.6%). The absorbed portion is largely metabolized, with less than 1% excreted unchanged in the urine. The terminal plasma half-life is 20-25 hours in most patients and is similar in those with renal impairment.
Oropharyngeal candidiasis:
Gastrointestinal tract candidiasis:
Occasionally, nausea and vomiting, diarrhea with long-term use, and rarely allergic reactions may occur.
In case of localized lesions of the mouth, a small amount of gel may be applied 2-4 times a day directly to the affected area with a clean finger. For best results, miconazole oral gel should be kept in contact with the affected area as long as possible. Treatment should be continued for at least a week after symptoms have disappeared. For oral candidosis, dental prostheses should be removed at night and brushed with the gel.
Apply the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Avoid concomitant treatment with terfenadine, astemizole, and cisapride, as miconazole may inhibit their metabolism, potentially leading to adverse effects. Miconazole may also delay the metabolism of phenytoin and cyclosporine, increasing the risk of toxicity.
Miconazole is contraindicated in patients with known hypersensitivity to the active ingredient.
There is no safety information regarding the use of miconazole oral gel during pregnancy. It should be avoided in pregnant women if possible, or the potential risks should be weighed against the possible benefits. Caution is advised when administering miconazole to nursing women, as many drugs are excreted in human milk.
When using miconazole with anticoagulants, monitor and adjust the anticoagulant effect as necessary. Miconazole and phenytoin plasma levels should also be monitored when used together. In infants and young children, ensure the gel does not obstruct the throat.
Store in a dry place away from light and heat. Keep out of reach of children
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.