Clovate N Cream | 0.05%+0.50%+100000IU | Uses, Dosage | ePharma
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Clobetasol Propionate 0.05% + Neomycin Sulphate 0.5% + Nystatin 1,00,000 IU. This preparation is-

  • Short courses treatment of recalcitrant eczemas.
  • Neurodermatitis.
  • Psoriasis (excluding widespread plaque psoriasis) where secondary bacterial infection or fungal infection is present, suspected, or likely to occur.
  • Other inflammatory conditions do not respond satisfactorily to less active steroids.

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Discount Price: ৳ 61.75
MRP: ৳ 65 5% Off

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✅ Description:

Clovate N Cream is a combination medication containing Nystatin, Clobetasol Propionate, and Neomycin Sulphate. It belongs to the group of medicines called Corticosteroids, Antifungals, and Antibiotics. It is primarily used to treat dermatoses (skin infections) that are resistant and have secondary bacterial or fungal infections.

However, there are certain conditions and precautions to consider before using Clovate N Cream :

It is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (such as herpes simplex and chickenpox), and perforated eardrum. It is important to contact your doctor before applying the cream.

Use Clovate N Cream with caution in patients with liver or kidney disease. It is advisable to consult your doctor before applying.

In pregnancy, Clovate N Cream is generally not recommended unless considered clearly necessary. For breastfeeding women, it is unknown whether the medication may pass through breast milk, so consulting your doctor is important before applying.

Clovate N Cream is not recommended for use in children under 2 years of age. It is essential to contact your doctor before applying.

Dosage adjustment is not required for the geriatric population, but greater sensitivity in some older individuals cannot be ruled out. It is always advisable to consult your doctor before applying.

The most common side effects of Clovate N Cream include skin rash, itching, redness, burning sensation, and contact dermatitis. If any of these symptoms worsen, it is recommended to contact your physician.

Safety Advices


Alcohol

No interaction found/established


Pregnancy
CONSULT YOUR DOCTOR

Clovate N Cream is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before applying.


Breastfeeding
CONSULT YOUR DOCTOR

Clovate N Cream should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.


Driving

No interaction found/established


Kidney
CAUTION

Clovate N Cream should be used with caution in patients with kidney disease. Contact your doctor before applying.


Liver
CAUTION

Clovate N Cream should be used with caution in patients with liver disease. Contact your doctor before applying.

Similar Products

✔️ Uses of Clovate N Cream

Psoriasis, Eczema, Severe inflammatory skin disorders

✔️ Side Effects of

Long-term widespread application or widespread treatment, similar to other topical corticosteroids, may result in sufficient systemic absorption and the symptoms of hypercortisolism. If an occlusive dressing is used, infants and young children are more likely to experience this effect. In particular, when the use of occlusive dressings or skin folds is impacted, intensive and prolonged treatment with highly active corticosteroid preparations can result in local atrophic changes in the skin, such as thinning, stretch marks, and superficial vasodilation. Topical steroids have reportedly been linked to hirsutism and changes in pigmentation.

✔️ How does Clovate N Cream work?

Clobetasol is a highly active corticosteroid that has topical anti-inflammatory action brought about partly by vasoconstriction and reduced collagen synthesis. Neomycin is an aminoglycoside antibiotic that binds to ribosomal 30S and 50S subunits of susceptible bacteria, thus inhibiting protein synthesis; it also causes misreading of the genetic codes on the mRNA template. Nystatin works by binding to ergosterol in the cell membrane of fungus resulting in a change in the cell wall permeability and leakage of cellular components.

✔️ Quick Suggestions:
  • Clovate N Cream must be applied as a thin layer on the affected area as prescribed by your doctor.
  • Do not use this medicine more often or for longer than advised by your doctor.
  • Before each application, wash the affected area with soap and water and dry well.
  • Avoid getting it in the eyes, mouth, or nose. Rinse with cold water if you accidentally get it in these areas.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
✔️ Indication of Clovate N Cream

Clovate N Cream is used to treat resistant dermatoses (skin infections) with secondary bacterial or fungal infection

✔️ Pharmacology

A topical corticosteroid with high potency is clobetasol propionate. It functions as a vasoconstrictor, anti-inflammatory, and antipruritic. Through a variety of anti-inflammatory effects, it prevents late-phase allergic reactions. Chemotaxis, eosinophil activation, and mast cell density are all decreased. Additionally, it lessens the production of cytokines and inhibits arachidonic acid metabolism.

✔️ Dosage & Administration of Clovate N Cream

The administration instructions for Clovate N Cream  are as follows:

  • Apply the cream sparingly to the affected area(s) once or twice daily until improvement occurs.
  • It is important to use a thin layer of cream on the affected area(s).
  • Therapy should be discontinued when control is achieved. If a longer course of treatment is necessary, it is recommended to review the patient's condition after 4 weeks.
  • Treatment should not be continued for more than 7 days without medical supervision.

For adults:

  • Apply a thin layer of the cream or ointment onto the affected area(s) 1-2 times daily until improvement occurs.
  • It is not recommended to use the cream for more than 7 days without medical supervision.

For children (2 years and older):

  • Apply a thin layer of the cream or ointment onto the affected area(s) 1-2 times daily until improvement occurs.
  • It is not recommended to use the cream for more than 7 days without medical supervision.

Please note that it is important to follow the instructions provided by your doctor or healthcare professional regarding the specific usage and duration of treatment with Clovate N Cream.

✔️ Interaction

After significant systemic absorption, neomycin sulfate can intensify and prolong the respiratory depression caused by neuromuscular blockers. Neomycin sulfate's systemic exposure is anticipated to be minimal when used as directed, and significant drug interactions are highly unlikely. There have been no reports of harmful interactions between nystatin and clobetasol propionate.

✔️ Contraindications

The drug is contraindicated in rosacea, acne vulgaris, and perioral dermatitis, primary skin viral infections (for example, herpes simplex, chickenpox), and those who are allergic to the preparation.

✔️ Pregnancy & Lactation

There is little data to prove the possible effects of topical neomycin on pregnancy and lactation. However, neomycin present in maternal blood can cross the placenta and, in theory, may pose risks of fetal toxicity, so its use during pregnancy and lactation is not recommended. The safety of clobetasol propionate in nursing mothers has not been established.

✔️ Precautions & Warnings

Long-term continuous topical treatment should be avoided as much as possible, especially in infants and children, because adrenal suppression is prone to occur even in the absence of occlusion. If applied to the eyelids, care must be taken to ensure that the preparation does not get into the eyes as it can cause glaucoma. If this medicine gets into your eyes, flush the affected eyes well with plenty of water.

✔️ Storage Conditions

Clovate N Cream should be stored at or below room temperature, away from direct heat or sunlight. Do not freeze. Also, keep it away from the reach of pets and children.

Frequently Asked Questions (FAQ)

The most common side effects of this medicine are skin rash, urticaria, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.

Clovate N Cream is used to treat resistant dermatoses (skin infections)

Clovate N Cream is not recommended for use in children under 2 years of age.

Clovate N Cream is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), perforated eardrum. Contact your doctor before applying.

No, do not stop using Clovate N Cream without consulting your doctor. Use Clovate N Cream in the dose and duration prescribed by the doctor. Usually, your condition will improve within a few days. If the condition worsens or does not improve within seven days, treatment and diagnosis should be re-evaluated. However, if the treatment is recommended to be continued for a longer duration, it should be done under medical supervision.

Clovate N Cream should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of it to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using Clovate N Cream unless it is used for treating infection of the hands. Avoid contact with the eyes.
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Check our pricing section for Clovate N Cream price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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