Cora-D | 500mg+200IU | 1 Strip

✔️ Composition

Cora-D Tablet: Calcium Carbonate USP 1250 mg (coral source) ≡ 500 mg elemental calcium + Vitamin D USP 200 IU

Cora-DX Tablet: Calcium Carbonate USP 1500 mg (coral source) ≡ 600 mg elemental calcium + Vitamin D USP 400 IU

Effervescent Tablet: Calcium Carbonate USP 1500 mg (coral source) ≡ 600 mg elemental calcium + Vitamin D3 400 IU

✔️ Dosage & Administration

Tablet: 1 tablet once or twice daily with water. Taking after meals ensures better absorption.

✔️ Drug Interactions

• Thiazide diuretics → ↑ risk of hypercalcemia (monitor serum calcium).
• Corticosteroids → may reduce calcium absorption.
• Cholestyramine/paraffin oil → may decrease vitamin D absorption.
• Tetracyclines → absorption reduced; take ≥2 hrs before or 4–6 hrs after calcium.
• Cardiac glycosides (e.g., digoxin) → ↑ toxicity risk; ECG and calcium levels must be monitored.
• Foods rich in oxalic acid (spinach, rhubarb) or phytic acid (cereals) may reduce calcium absorption

✔️ Side Effects

GI irritation (nausea, constipation, abdominal discomfort)

Rare: hypercalcemia, irregular heartbeat, drowsiness, allergic rash

High doses may cause vitamin D–D-related adverse effects

✔️ Overdose Effects

Excess intake may cause:

Hypercalcemia → nausea, vomiting, constipation, abdominal pain, confusion, fatigue, irregular heartbeat

Long-term high calcium → kidney damage, soft tissue calcification

Treatment: Discontinue calcium, stop interacting drugs, rehydration, and specific therapies (loop diuretics, bisphosphonates, calcitonin, corticosteroids).

✔️ Contraindications

• Hypercalcemia or hyperparathyroidism
• Hypercalciuria or kidney stones
• Severe renal insufficiency
• Known hypersensitivity to ingredients
• Concurrent digoxin therapy (requires monitoring)

✔️ Pregnancy & Lactation

• Safe when taken within limits: ≤1500 mg calcium & 600 IU vitamin D daily.
• An overdose can cause fetal hypercalcemia or developmental issues.
• Calcium and vitamin D3 pass into breast milk – additional supplementation for infants should be considered cautiously.

✔️ Precautions & Warnings

• Long-term use: Monitor serum calcium and renal function.
• Use cautiously in:
• Elderly patients on cardiac glycosides or diuretics
• Patients prone to kidney stones
• Sarcoidosis (due to altered vitamin D metabolism)
• Immobilized osteoporosis patients (risk of hypercalcemia)
• Avoid concurrent high-dose calcium or vitamin D unless under medical supervision.

✔️ Storage:

Store below 30°C, away from light & moisture.

Keep out of children’s reach.