St. John’s Wort is commonly used to treat mild to moderate depression and associated conditions such as anxiety, fatigue, loss of appetite, and insomnia. The main components, Hypericin and Hyperforin, are responsible for its antidepressant effects. Although the exact mechanism is unknown, it is believed to inhibit the reuptake of serotonin and noradrenaline, inhibit Monoamine Oxidase (MAO), up-regulate serotonin receptors, and reduce depression.
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Rimodep Capsule is a specialized formulation that contains a standardized extract of St. John’s Wort, renowned for its effectiveness in treating depression. The essential active components in St. John’s Wort, including hypericin, hyperforin, hyperoside, quercitrin, and vitamin C, contribute to its therapeutic properties. Jonort, found in Rimodep Capsule, demonstrates antidepressant effects by preventing the reuptake of neurotransmitters such as serotonin, dopamine, noradrenaline, γ-aminobutyric acid (GABA), and L-glutamate. Additionally, it exerts inhibitory actions on Monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT).
The recommended dose for St. John’s Wort capsule in adults is 1 capsule three times daily or as prescribed by the physician.
St. John’s Wort is generally safe, but it may occasionally cause side effects such as dry mouth, dizziness, constipation, and diarrhea.
Overdose symptoms may include dry mouth, dizziness, and diarrhea.
Not recommended during pregnancy due to potential risks to the infant. Breastfeeding while using this drug is also not recommended.
Store in a cool and dry place, away from direct sunlight.
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