Ascobex 250mg Chewable Tablet

✔️ Uses of Ascobex 250mg Chewable Tablet

• Treatment of Vitamin C Deficiency.

✔️ How does Ascobex 250mg Chewable Tablet work?

Vitamin C is a vitamin that provides essential nutrients.

✔️ Side Effects of Ascobex 250mg Chewable Tablet

No common side effects seen

✔️ Quick Suggestions:

• Drink plenty of liquids while you are taking ascorbic acid.
• Do not take vitamin C and tell your doctor If you are pregnant or breast-feeding.
• Do not take this drug If you are allergic to Vitamin C.
• Stop taking the drug and call your doctor at once if you have: joint pain, weakness or tired feeling, weight loss, stomach pain, chills, fever, increased urge to urinate, painful or difficult urination, severe pain in your side or lower back, blood in your urine.

✔️ Indications:

Ascorbic acid, also known as vitamin C, is utilized to prevent or address insufficient levels of vitamin C in individuals with inadequate dietary intake. For those maintaining a normal diet, additional ascorbic acid is usually unnecessary. Insufficient vitamin C levels can lead to a condition called scurvy, characterized by symptoms like rash, muscle weakness, joint pain, fatigue, and tooth loss.

Vitamin C holds a crucial role in maintaining various aspects of bodily health. It is essential for the well-being of skin, cartilage, teeth, bones, and blood vessels. Furthermore, vitamin C acts as an antioxidant, playing a vital role in protecting the body's cells from damage.

✔️ Pharmacology

Vitamin C, a water-soluble vitamin, is readily absorbed from the gastrointestinal tract and is widely distributed throughout the body. It plays a crucial role in biological oxidations and reductions associated with cellular respiration. Vitamin C is essential for the formation of collagen and intracellular materials.

When dietary intake is inadequate and the body's increased demand is not met, a deficiency in vitamin C may develop. This insufficiency can lead to a well-defined condition known as scurvy. Scurvy is characterized by symptoms such as capillary fragility, bleeding (especially from small blood vessels and the gums), anemia, abnormalities in cartilage and bone, and impaired wound healing—all of which result from the deficiency of vitamin C.

✔️ Dosage & Administration of Ascobex 250mg Chewable Tablet

Oral Administration:

• Prevention of Scurvy: 1 tablet daily.
• Treatment of Scurvy: 1-2 tablets daily; the dose may be increased based on the severity of the condition.
• Reduction of Stroke Risk in the Elderly: 1-2 tablets daily.
• Other Cases: 1 tablet daily or as directed by the physician.
• Maximum Safe Dose: 2000 mg daily in divided doses.

Parenteral Administration:

• Preferred Route: Vitamin C is usually administered orally. Parenteral routes (IM, IV, or subcutaneous) are considered when oral administration is not feasible or malabsorption is suspected.
• Best Utilization: IM administration is preferred among parenteral routes.
• Intravenous Injection: Dilution into a large volume parenteral (Normal Saline, Water for Injection, or Glucose) is recommended to minimize adverse reactions.
• Average Protective Dose for Adults: 70 to 150 mg daily.
• Scurvy Treatment: Doses of 300 mg to 1 g daily are recommended; up to 6 g parenterally to normal adults without toxicity evidence.
• Wound Healing Enhancement: 300 to 500 mg daily for a week or ten days preoperatively and postoperatively.
• Burn Treatment: For severe burns, daily doses of 1 to 2 g are recommended.
• Increased Need for Vitamin C: In conditions with increased vitamin C requirements, three to five times the daily optimum allowances may be adequate.
• Visual Inspection: Parenteral drug products should be visually inspected for particulate matter and discoloration before administration if the solution and container permit.

✔️ Interaction

Incompatible drug combinations in solution with ascorbic acid include:

1. Aminophylline
2. Bleomycin
3. Erythromycin lactobionate
4. Nafcillin
5. Nitrofurantoin sodium
6. Conjugated estrogen
7. Sodium bicarbonate
8. Sulphafurazole diethanolamine
9. Chloramphenicol sodium succinate
10. Chlorothiazide sodium
11. Hydrocortisone sodium succinate

On the other hand, ascorbic acid has positive interactions:

• It improves iron absorption from the gastrointestinal system.
• It increases the apparent half-life of paracetamol.

✔️ Contraindications

Do not take Ascobex 250mg Chewable Tablet if you are allergic to any of its components.

✔️ Pregnancy & Lactation

The drug is safe in normal doses in pregnant women, but a daily intake of 5 gm or more is reported to have caused abortion. The drug may be taken safely during lactation.

✔️ Precautions & Warnings

• If you are pregnant, breastfeeding, or have existing medical conditions such as diabetes, hypertension, kidney, or liver problems, it is crucial to consult your doctor before using this supplement.
• Inform your healthcare provider if you are taking other medications or supplements, or following any complementary or integrative health approaches.
• If you are scheduled for surgery or an operation, you may be advised to discontinue the supplement at least 2-3 weeks before the procedure. Consult with your healthcare provider for guidance.
• Vitamin supplements are meant to complement the diet and should not be considered a substitute for a well-balanced, varied diet, and a healthy lifestyle.

✔️ Storage Conditions

Should be stored in a dry place below 30˚C.