Sinalax Oral Powder (10pcs Box)

✔️ Uses:

• Constipation
• Liver Encephalopathy

✔️ How does Sinalax Oral Powder work?

Sinalax Oral Powder belongs to the group of medicines known as laxatives, primarily used for the treatment of constipation. Additionally, it finds application in the prevention of hepatic encephalopathy, a condition characterized by decreased brain function resulting from liver disease.

Sinalax Oral Powder contains Lactitol Monohydrate, a disaccharide sugar. Its mode of action involves breaking down into low-molecular-weight organic acids within the colon. This process leads to an increase in osmotic pressure, resulting in greater water content in the stool and an increase in stool volume. These changes make the stool softer and easier to pass, thereby providing relief from constipation.

In patients with hepatic encephalopathy, Lactitol serves to lower the pH in the colon. This action suppresses the absorption of unionized ammonia and other toxins. Furthermore, Lactitol enhances the excretion of nitrogen through feces, contributing to the management of hepatic encephalopathy.

Overall, Sinalax Oral Powder is an effective medication for alleviating constipation and preventing the progression of hepatic encephalopathy in individuals with liver disease.

✔️ Side Effects of Sinalax Oral Powder

• At the beginning of treatment, Lactitol may cause abdominal discomfort such as flatulence, pain, cramps, or a sensation of fullness.
• These effects typically decrease or disappear after a few days.
• Occasional side effects include nausea or anal pruritus.

✔️ Quick Suggestions:

• Balanced Diet: Maintain a balanced diet that includes fresh fruits and vegetables.
• Hydration: Stay hydrated by drinking enough water and other fluids.
• Regular Exercise: Incorporate regular exercise into your routine to stay fit.
• Adequate Sleep: Ensure you get enough quality sleep to support overall health.
• Listen to Your Body: Pay attention to your body's signals and make time to empty your bowels when necessary.
• Fiber-Rich Foods: Consume foods high in fiber, such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados). Fiber:
• Promotes healthy bowel movement and improves bowel function.
• Lubricates the intestinal lining, aiding in the easy passing of stools.
• May help with digestion problems like gas and bloating.
• Provides gentle and effective relief from constipation.
• Adequate Fluid Intake: While taking Lactitol Monohydrate, maintain adequate fluid intake to support its effectiveness in relieving constipation.

✔️ Indication

• Used to treat chronic idiopathic constipation (CIC).
• Also used for acute and chronic portal encephalopathy.

✔️ Pharmacology

• Lactitol Monohydrate is a disaccharide derivative composed of galactose and sorbitol.
• It is minimally absorbed and not hydrolyzed in the gastrointestinal tract.
• It reaches the colon unaltered, where it is broken down by intestinal flora.
• This breakdown increases osmotic pressure in the colon, leading to an increase in stool water content and volume, resulting in a laxative effect.

✔️ Dosage & Administration of Sinalax Oral Powder

• In constipation:
  • Adults: The initial daily dosage is 20 g, which may be reduced to 10 g after a few days.
  • Children: Dosage varies based on age and body weight.
• In portal systemic encephalopathy: Dosage should be adjusted based on disease severity and individual response.

✔️ Interaction

• Stomach settling agents and neomycin should not be administered concurrently with Lactitol in cirrhotic patients with portal systemic encephalopathy.
• Lactitol may increase potassium loss caused by certain drugs, and enhance the toxic effects of glycosides in patients receiving concurrent treatment.

✔️ Contraindications

Contraindicated in patients with known hypersensitivity to any of its components.

✔️ Pregnancy & Lactation

• The systemic absorption of lactitol following oral administration is minimal.
• It's unknown whether maternal use will result in fetal exposure to the drug.
• There is no data available on the presence of lactitol in human or animal milk, its effects on the breastfed infant, or its effects on milk production.

✔️ Precautions & Warnings

• Elderly or debilitated patients receiving long-term treatment with lactitol should have their serum electrolytes monitored regularly.
• Pre-existing fluid or electrolyte imbalances should be corrected before starting treatment.
• Prolonged use of laxatives without interruption should be avoided.

✔️ Storage Conditions

• Store below 30°C, protected from light and moisture.
• Keep the medicine out of the reach of children.