Pantonix 40mg Tablet

✔️ Uses of Pantonix 40mg Tablet

Treatment of-

• Heartburn
• Gastroesophageal Reflux Disease
• Peptic Ulcer Disease

✔️ How Pantonix 40mg Tablet works?

An inhibitor of the proton pump is Pantonix 40mg Tablet. By blocking the proton pump protein membrane H+K+Atpase from moving across the stomach lining, it lowers gastric acid secretion. As a result, it repairs existing ulcers and esophageal lesions, prevents ulcers from getting worse, and relieves uncomfortable GI tract symptoms. (such as acidity, heartburn, and acid reflux).

✔️ Side Effects of Pantonix 40mg Tablet

• Headache
• Diarrhoea
• Nausea
• Abdominal pain
• Vomiting
• Flatulence
• Feeling weak
• Fragile bones (risk of bone fracture)
• Nausea or vomiting
• Diarrhea
• Constipation
• Stomach pain
• Flatulence
• Dry mouth
• Dizziness
• Arthralgia (joint pain)

✔️ Quick Suggestions:

• It is recommended to take a Pantonix 40mg Tablet one hour before a meal, ideally in the morning.
• It is a medication that is well-tolerated and lasts a very long period.
• If you experience reduced urine, edema (swelling brought on by fluid retention), lower back discomfort, nausea, exhaustion, rash, or fever, call your doctor immediately once. These could be kidney-related symptoms.
• Try to elevate your bedhead before you go to sleep so that your head and chest are higher than your feet. Use one elevated block rather than a pile of cushions. This will prevent stomach acid from reentering your food pipe.
• Do not consume alcohol or smoke cigarettes. Alcohol can increase the amount of stomach acid produced, causing acid reflux and heartburn. On the other hand, nicotine use harms the sphincter, a valve that stops stomach acid from flowing back into the food pipe.
• If you get a fever, watery diarrhea, or persistent stomach pain, call your doctor right immediately.
• After taking it for 14 days, if you still don't feel better, let your doctor know as you could have another issue that needs care.
• Pantonix 40mg Tablet usage for an extended period of time may result in weak bones and a mineral shortage, particularly magnesium. As directed by your doctor, get enough calcium and magnesium in your diet or as supplements.
• Without consulting your doctor, do not discontinue taking your prescription.

✔️ Indications of Pantonix 40mg Tablet

Pantonix 40 is prescribed when acid secretion suppression is beneficial to the patient's health such as-

Ulcers in the Stomach and Intestines:

• Gastric ulcers are lesions in the stomach and duodenum's lining that are painful and damaging. (the beginning of the small intestine). These happen when too much stomach acid damages the stomach's and the small intestine's protective layer. The medication Pantonix 40mg Tablet is used to treat stomach and small intestinal ulcers.
  Stomach Acid Reflux Disease

Gastroesophageal Reflux Disease:

• The condition known as gastroesophageal reflux disease (GERD) is brought on by persistent reflux of stomach acid into the food pipe. The primary signs and symptoms of GERD include heartburn, swallowing issues, and regurgitation (when food, fluids, or stomach acid runs back up from the stomach and into the mouth). The Pantonix 40mg Tablet treats GERD by reducing stomach acid production.

Erosive Esophagitis:

The lining of the tube that transports food from the throat to the stomach might become inflamed and swollen if you have erosive esophagitis. It happens when too much stomach acid leaks back into the food line, causing irritation and damage. Pantonix 40mg Tablet work by reducing the production of stomach acid to treat erosive esophagitis.

Zollinger-Ellison Syndrome:

• Tumors develop in the duodenum and pancreas, two organs that are situated below the stomach, as a result of the illness known as Zollinger-Ellison Syndrome. (the first part of the small intestine). These tumors release a chemical, which prompts the stomach to create too much acid. To lessen the excessive stomach acid produced by tumors, Pantonix 40mg Tablet is utilized.

Helicobacter Pylori Infection:

A form of a bacterium called Helicobacter pylori that infects the stomach is what leads to Helicobacter Pylori Infection. It is a relatively frequent illness that results in swelling of the food pipe, small intestine, and stomach lining. Antibiotics are also used in conjunction with Pantonix 40mg Tablet to treat and prevent this illness.

✔️ Pharmacology

Proton pump inhibitor Pantonix 40 inhibits the last stage of gastric acid production by covalently binding to the H+/K+ATPase enzyme system on the surface of the gastric parietal cell. Whether the stimulus is present for less than 24 hours or for more than 24, this effect reduces the formation of both basal and induced stomach acid.

✔️ Dosage & Administration of Pantonix 40mg Tablet

Benign Stomach Ulcer:

• 40 mg once a day in the morning for 4 weeks, then continued if not entirely healed for an additional 4 weeks.

GERD: 

• 20–40 mg daily in the morning for four weeks, maintained for another four weeks if not totally resolved; maintenance dosage is 20 mg daily, which may be raised to 40 mg daily.

Duodenal Ulcer: 

• Take 40 mg every morning for two weeks, then take it again if necessary.

Helicobacter Pylori-related Duodenal Ulcer: 

• 40 mg of pantoprazole twice daily is advised in conjunction with the antibiotics listed below:
• For a week, use either Amoxycillin 1 g and Clarithromycin 500 mg twice daily, or Clarithromycin 250 mg and Metronidazole 400 mg twice daily.

For patients who need long-term NSAID treatment: 

• 20 mg per day is recommended as a preventative measure for stomach or duodenal ulcers linked to NSAID use.

Syndrome of Zollinger-Ellison:

• Elderly patients may only get 40 mg per day at first; daily dosages beyond 80 mg are administered in two split doses.

✔️ Interaction

Iron supplements, blood thinners (clopidogrel, warfarin), antifungals (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV medications (atazanavir, nelfinavir), antibiotics (ampicillin, rifampicin), heart medications (digoxin), and anti-cancer medications might all interact with pantone 40. (methotrexate). If you use these medications, tell your doctor.

The antidepressant St. John's wort plant interacts with Pantonix 40. This plant could have an impact on how Pantonix 40 functions. Therefore, avoid taking Pantonix 40 with it.

Patients who have colitis caused by Clostridium difficile, liver problems, bone fractures, low vitamin B12 levels (anemia), or low magnesium levels shouldn't use Pantonix 40. (hypomagnesemia).

✔️ Contraindications

Pantoprazole is not recommended for those who have a known hypersensitivity to any of the formulation's ingredients.

✔️ Pregnancy & Lactation

Risk Overview The information that is currently available from published observational studies does not support a link between pantoprazole use and significant abnormalities or other undesirable pregnancy outcomes. Pantoprazole did not appear to have any negative developmental effects in investigations on animal reproduction. The administration of pantoprazole during organogenesis in pregnant animals was studied in reproduction studies in rats at oral doses up to 450 mg/kg/day (roughly 88 times the recommended human dose) and rabbits at oral doses up to 40 mg/kg/day (roughly 16 times the recommended human dose), and there was no evidence of harm to the fetus due to pantoprazole in this study.

✔️ Precautions & Warnings

• If you are allergic to Pantonix 40 or taking proton pump inhibitors, have stomach cancer, liver illness, low magnesium levels (osteoporosis), low vitamin B12 levels, are pregnant or planning a pregnancy, or are a nursing mother, you should not take Pantonix 40.
• Iron supplements, ampicillin antibiotic, a warfarin blood thinner, ketoconazole antifungal, atazanavir, nelfinavir, and anti-HIV medication all have the potential to interact with Pantonix 40. (methotrexate).
• If you use these medications, tell your doctor. Long-term usage of Pantonix 40 raises the risk of magnesium, Vitamin B12, and lupus erythematosus, an inflammatory disorder in which the immune system destroys its own tissues.
• Consuming Pantonix 40 may conceal gastric cancer symptoms, therefore if you have any significant stomach discomfort or gastric bleeding (blood in your mucus or stools), call your doctor right once.

✔️ Storage Conditions

Keep away from light and heat in a dry area. Keep out of children's reach.